Incorporation of regional information in optimal 3-D graph search with application for intraretinal layer segmentation of optical coherence tomography images

Mona Haeker; Xiaodong Wu; Michael Abràmoff; Randy Kardon; Milan Sonka

doi:10.1007/978-3-540-73273-0_50

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Conference proceeding

Incorporation of regional information in optimal 3-D graph search with application for intraretinal layer segmentation of optical coherence tomography images

Mona Haeker, Xiaodong Wu, Michael Abràmoff, Randy Kardon and Milan Sonka

Information processing in medical imaging : proceedings of the ... conference, Vol.20, pp.607-618

2007

DOI: 10.1007/978-3-540-73273-0_50

PMID: 17633733

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Abstract

We present a method for the incorporation of regional image information in a 3-D graph-theoretic approach for optimal multiple surface segmentation. By transforming the multiple surface segmentation task into finding a minimum-cost closed set in a vertex-weighted graph, the optimal set of feasible surfaces with respect to an objective function can be found. In the past, this family of graph search applications only used objective functions which incorporated "on-surface" costs. Here, novel "in-region" costs are incorporated. Our new approach is applied to the segmentation of seven intraretinal layer surfaces of 24 3-D macular optical coherence tomography images from 12 subjects. Compared to an expert-defined independent standard, unsigned border positioning errors are comparable to the inter-observer variability (7.8 +/- 5.0 microm and 8.1 +/- 3.6 microm, respectively).

Algorithms

Reproducibility of Results

Retina - cytology

Artificial Intelligence

Humans

Image Interpretation, Computer-Assisted - methods

Sensitivity and Specificity

Imaging, Three-Dimensional - methods

Image Enhancement - methods

Retinoscopy - methods

Tomography, Optical Coherence - methods

Pattern Recognition, Automated - methods

Details

Title: Subtitle: Incorporation of regional information in optimal 3-D graph search with application for intraretinal layer segmentation of optical coherence tomography images
Creators: Mona Haeker - Department of Electrical & Computer Engineering, University of Iowa, Iowa City, IA 52242, USA. mona-haeker@uiowa.edu
Xiaodong Wu
Michael Abràmoff
Randy Kardon
Milan Sonka
Resource Type: Conference proceeding
Publication Details: Information processing in medical imaging : proceedings of the ... conference, Vol.20, pp.607-618
DOI: 10.1007/978-3-540-73273-0_50
PMID: 17633733
NLM abbreviation: Inf Process Med Imaging
ISSN: 1011-2499
Publisher: Germany
Language: English
Date published: 2007
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Iowa Neuroscience Institute; Radiation Oncology; Injury Prevention Research Center; Ophthalmology and Visual Sciences
Record Identifier: 9983980003502771

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