Lab on a Chip Sensor Platform for Explosives and CBW Toxin Detection

G.E Collins; A Haes; Q Lu; B Giordano

doi:10.1109/MSHS.2006.314338

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Conference proceeding

Lab on a Chip Sensor Platform for Explosives and CBW Toxin Detection

G.E Collins, A Haes, Q Lu and B Giordano

2006 IEEE International Workshop on Measurement Systems for Homeland Security, Contraband Detection and Personal Safety, pp.2-4

10/2006

DOI: 10.1109/MSHS.2006.314338

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Abstract

There has been significant interest in the adaptation of lab on a chip devices for the separation and detection of chemical and biological toxins. Potential toxic and/or hazardous analytes of concern in our program include BWA protein toxins,e.g., SEB and ricin, ingestible CW toxins, e.g. alkaloids and rat poisons, and nitroaromatic explosives indicative of IED's. Discussion will center around our efforts to enhance sensitivity and selectivity on a microchip by incorporation of micro-solid-phase extraction, microchip bubble-cell long pathlength UV detection, organically-modified sol-gel materials for electrochromatography, protein recognition aptamers, and microfluidic-based displacement immunoassays

alkaloids

antibody

aptamer

capillary electrophoresis

displacement immunoassay

explosives

lab on a chip

microchip

ricin

staphylococcus entertoxin B

Details

Title: Subtitle: Lab on a Chip Sensor Platform for Explosives and CBW Toxin Detection
Creators: G.E Collins - Naval Res. Lab
A Haes
Q Lu
B Giordano
Resource Type: Conference proceeding
Publication Details: 2006 IEEE International Workshop on Measurement Systems for Homeland Security, Contraband Detection and Personal Safety, pp.2-4
DOI: 10.1109/MSHS.2006.314338
Publisher: IEEE
Language: English
Date published: 10/2006
Academic Unit: Chemistry
Record Identifier: 9984216721202771

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