Conference proceeding
Modeling the Geometry, Hemodynamics and Tissue Mechanics of Cerebral Aneurysms
Advances in Bioengineering, pp.397-398
ASME 2004 International Mechanical Engineering Congress and Exposition, Anaheim, California, USA, Nov. 13 - 19, 2004
01/01/2004
DOI: 10.1115/IMECE2004-60024
Abstract
The relationship between cerebral aneurysm geometry and biomechanics was investigated. Human cerebral aneurysm geometry was reconstructed from computed tomography angiography (CTA) and refined. Various indices of global geometric (size and shape) features were computed based on differential and computational geometry techniques. Computational fluid dynamics (CFD) simulations were performed to model both steady and pulsatile blood flow in the aneurysm and surrounding vasculature. Hemodynamic indices such as wall shear stress, pressure and particle residence time were obtained. Nonlinear finite element method (FEM) and a reported finite strain constitutive model were employed to estimate the distribution of mechanical stress in the aneurysm wall under static pressure. Shear stress, sac pressure and mechanical stress correlated better with lesion shape while particle residence time correlated better with lesion size.
Details
- Title: Subtitle
- Modeling the Geometry, Hemodynamics and Tissue Mechanics of Cerebral Aneurysms
- Creators
- Baoshun Ma - University of IowaRobert Harbaugh - Pennsylvania State UniversityJia Lu - University of IowaMadhavan Raghavan - University of Iowa
- Resource Type
- Conference proceeding
- Publication Details
- Advances in Bioengineering, pp.397-398
- Conference
- ASME 2004 International Mechanical Engineering Congress and Exposition, Anaheim, California, USA, Nov. 13 - 19, 2004
- Publisher
- ASMEDC
- DOI
- 10.1115/IMECE2004-60024
- ISSN
- 0360-9960
- Language
- English
- Date published
- 01/01/2004
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Mechanical Engineering
- Record Identifier
- 9984196510902771
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