Multi-scale AM-FM for lesion phenotyping on age-related macular degeneration

E.S Barriga; V Murray; C Agurto; M.S Pattichis; S Russell; M.D Abramoff; H Davis; P Soliz

doi:10.1109/CBMS.2009.5255398

Back

Conference proceeding

Multi-scale AM-FM for lesion phenotyping on age-related macular degeneration

E.S Barriga, V Murray, C Agurto, M.S Pattichis, S Russell, M.D Abramoff, H Davis and P Soliz

2009 22nd IEEE International Symposium on Computer-Based Medical Systems, pp.1-5

08/2009

DOI: 10.1109/CBMS.2009.5255398

View Online

Abstract

Age-related macular degeneration (AMD) is the most common cause of visual loss in the United States and is a growing public health problem. The presence and severity of AMD in current epidemiological studies is detected by the grading of color stereoscopic fundus photographs. The purpose of this study was to show that a mathematical technique, amplitude-modulation frequency modulation (AM-FM) can be used to generate multi-scale features for classifying pathological structures, such as drusen, on a retinal image. AM-FM features were calculated for N=120 40times40 regions from 5 retinal images presenting with age-related macular degeneration. The results show that with this technique, drusen can be differenced from normal retinal structures by more than three standard deviations using the AM-FM histograms. In addition, by using different color spaces highly accurate classification of structures of the retina is achieved. These results are the first step in the development of an automated AMD grading system.

Histograms

Frequency modulation

Degenerative diseases

Cities and towns

Retina

Frequency estimation

Biomedical measurements

Lesions

Pigmentation

Public healthcare

Macular Degeneration

AM-FM

Details

Title: Subtitle: Multi-scale AM-FM for lesion phenotyping on age-related macular degeneration
Creators: E.S Barriga - VisionQuest Biomed., LLC, Albuquerque, NM, USA
V Murray - Dept. of Electr. & Comput. Eng., Univ. of New Mexico, Albuquerque, NM, USA
C Agurto - Dept. of Electr. & Comput. Eng., Univ. of New Mexico, Albuquerque, NM, USA
M.S Pattichis - Dept. of Electr. & Comput. Eng., Univ. of New Mexico, Albuquerque, NM, USA
S Russell - Dept. of Ophthalmology & Visual Sci., Univ. of Iowa, Iowa City, IA, USA
M.D Abramoff - Dept. of Ophthalmology & Visual Sci., Univ. of Iowa, Iowa City, IA, USA
H Davis - VisionQuest Biomedical
P Soliz - VisionQuest Biomed., LLC, Albuquerque, NM, USA
Resource Type: Conference proceeding
Publication Details: 2009 22nd IEEE International Symposium on Computer-Based Medical Systems, pp.1-5
Publisher: IEEE
DOI: 10.1109/CBMS.2009.5255398
ISSN: 1063-7125
Language: English
Date published: 08/2009
Academic Unit: Ophthalmology and Visual Sciences; Electrical and Computer Engineering; Roy J. Carver Department of Biomedical Engineering
Record Identifier: 9983806285702771

Metrics

19 Record Views