Conference proceeding
Multifocal visual evoked potential in optic neuropathies and homonymous hemianopias
Perimetry Update 2002/2003: Proceedings of the XVth International Perimetric Society Meeting, Stratford-upon-Avon, England, June 26-29, 2002, pp.265-274
04/16/2002
Abstract
Purpose: To validate multifocal visual evoked potential (mfVEP) testing in patients with neuroophthalmological disorders. Methods: We tested 33 normals and 20 patients with documented lesions of the optic nerve and retrochiasmatic visual pathways. Fifteen of the patients had optic neuropathies and five had hemianopias. All patients had Humphrey SITA 24-2 testing and the mfVEP using the Opera mfVEP system. Visual field defects were defined for conventional automated perimetry as having three contiguous abnormal test locations at the p < 0.05 level or worse in a clinically suspicious area. Based on the testing of normals, all mfVEP results used the same criteria except abnormality at the p < 0.01 level was used. Amplitude information of three types was used for the mfVEP analysis: 1. signal of less than 90 nV; 2. probability plot data; and 3. intereye asymmetry comparison. Results: Using three contiguous abnormal test locations atp < 0.01, 12-18% of normals have defects with mfVEP. Conventional automated perimetry in normals showed 15% to have visual field defects. We found that mfVEP showed similar deficits to conventional automated perimetry in the non-demyelinating optic neuropathy patients. In recovered optic neuritis patients, mfVEP was superior. Three of five patients with hemianopias were missed by mfVEP. Conclusions: In non-demyelinating optic neuropathies, mfVEP results correlate very well with perimetry. In demyelinating optic neuropathies, mfVEP is a very sensitive test. MfVEP did not appear to be a good test for detecting hemianopias in our small sample. It appears that a larger database of normals is needed to better separate patients with visual field defects from normal subjects.
Details
- Title: Subtitle
- Multifocal visual evoked potential in optic neuropathies and homonymous hemianopias
- Creators
- Michael WallKimberly WoodwardTodd Sleep
- Resource Type
- Conference proceeding
- Publication Details
- Perimetry Update 2002/2003: Proceedings of the XVth International Perimetric Society Meeting, Stratford-upon-Avon, England, June 26-29, 2002, pp.265-274
- Publisher
- Kugler Publications
- Language
- English
- Date published
- 04/16/2002
- Description audience
- Academic
- Academic Unit
- Ophthalmology and Visual Sciences; Neurology
- Record Identifier
- 9984186925502771
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