Conference proceeding
Online measurement of urea concentration in spent dialysate during hemodialysis
Proceedings of SPIE, Vol.4624(1), pp.95-105
Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II
05/24/2002
DOI: 10.1117/12.468312
Abstract
We describe on-line optical measurements of urea concentration during the regular hemodialysis treatment of several patients. The spectral measurements were performed in the effluent dialysate stream after the dialysis membrane using an FTIR spectrometer equipped with a flow-through cell. Spectra were recorded across the 5000-4000 cm
(2.0-2.5 micrometers at 1-minute intervals. Optically determined concentrations matched concentrations obtained from standard chemical assays with a root-mean-square error of 0.29 mM for urea (0.8 mg/dl urea nitrogen), 0.03 mM for creatinine, 0.11 mM for lactate, and 0.22 mM for glucose. The observed concentration ranges were 0-11 mM for urea, 0-0.35 mM for creatinine, 0-0.75 mM for lactate, and 9-12.5 mM for glucose.
Details
- Title: Subtitle
- Online measurement of urea concentration in spent dialysate during hemodialysis
- Creators
- Jonathon T Olesberg - Univ. of Iowa (USA)Ben Armitage - Univ. of Iowa (USA)Mark A Arnold - Univ. of Iowa (USA)Michael Flanigan - College of Medicine/Univ. of Iowa (USA)
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.4624(1), pp.95-105
- Conference
- Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II
- DOI
- 10.1117/12.468312
- ISSN
- 0277-786X
- Language
- English
- Date published
- 05/24/2002
- Academic Unit
- Internal Medicine; Fraternal Order of Eagles Diabetes Research Center; Center for Biocatalysis and Bioprocessing; Chemistry; Physics and Astronomy
- Record Identifier
- 9984216682502771
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