Conference proceeding
Pushing the limits of an O-18 water target
APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY, Vol.680(1), pp.1098-1101
AIP CONFERENCE PROCEEDINGS
01/01/2003
DOI: 10.1063/1.1619899
Abstract
A gridded-niobium target was constructed for the improvement of routine [F-18]-fluorine production from O-18-enriched water on a CTI RDS 112 cyclotron. Niobium was chosen for its inertness and excellent thermal properties. The target volume consists of a 400muL (active volume) niobium chamber mounted with a single entrance foil supported against an array of 3mm hexagonal holes with 0.25mm aluminum septa, machined by EDM. The target operates at high beam currents and elevated pressures and temperatures with significant reductions in maintenance intervals. Several diagnostic tools such as autoradiography, activation and neutron lodging optimize the performance and yield of the target. Entrance foils including Havar and Nb are used to assess the [F-18] chemical compatibility, with FDG synthesis as the test reaction. The gridded, single-foiled niobium target chamber appears to be an improvement compared to a standard double-foiled helium cooled water target used with RDS cyclotrons.
Details
- Title: Subtitle
- Pushing the limits of an O-18 water target
- Creators
- J A NyeD W DickR J Nickles
- Contributors
- J L Duggan (Editor)I L Morgan (Editor)
- Resource Type
- Conference proceeding
- Publication Details
- APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY, Vol.680(1), pp.1098-1101
- Publisher
- Amer Inst Physics
- Series
- AIP CONFERENCE PROCEEDINGS
- DOI
- 10.1063/1.1619899
- ISSN
- 0094-243X
- eISSN
- 1551-7616
- Number of pages
- 4
- Language
- English
- Date published
- 01/01/2003
- Academic Unit
- Radiology; Pharmaceutical Sciences and Experimental Therapeutics
- Record Identifier
- 9984318798402771
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