Conference proceeding
Segmental bone defect repair using sintered, porous ceramics
Key Engineering Materials, Vol.Volumes 218-220, pp.409-412
11/2001
DOI: 10.4028/www.scientific.net/kem.218-220.409
Abstract
The use of sintered, porous ceramics as alternatives to autograft was studied in a segmental defect model. One hundred and eight rabbits were entered into the study. A one centimeter mid-diaphyseal segmental defect was created and stabilized with an external fixator. The defect was filled with a porous sintered Ceramic, autograft or left open. Animals were radiographed weekly and sacrificed at 6 or 8 weeks post-operatively. Torsional strengths of hydroxyapatite, tricalcium phosphate, and autograft groups were as strong as or stronger than there internal control limbs at 6 weeks post surgery, where as the open control group was 50% of its internal control limb. The alumina group at 6 weeks was 84% of normal. At 8 weeks, all ceramic groups had significantly higher torsional strengths than internal controls. The sintered, porous ceramics used in this study are good alternatives to autograft in repair of diaphyseal segmental defects.
Details
- Title: Subtitle
- Segmental bone defect repair using sintered, porous ceramics
- Creators
- D C FredericksJ A BobstE B PetersenJ V NepolaB HeckendorfB NorbergY KoJ J Cassidy
- Resource Type
- Conference proceeding
- Publication Details
- Key Engineering Materials, Vol.Volumes 218-220, pp.409-412
- DOI
- 10.4028/www.scientific.net/kem.218-220.409
- ISSN
- 1013-9826
- eISSN
- 1662-9795
- Language
- English
- Date published
- 11/2001
- Academic Unit
- Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center
- Record Identifier
- 9984303972302771
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