Conference proceeding
Small Scale Flow Structure Evolution During Mechanical Heart Valve Closure
Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, Vol.1
ASME 2013 Summer Bioengineering Conference, Sunriver, Oregon, USA, Jun. 26 - 29, 2013
06/26/2013
DOI: 10.1115/SBC2013-14603
Abstract
Despite half a century of use, mechanical heart valves still require further research to reduce the non-physiologic nature of the flow field, which is the source of potential medical complications, of which the most serious complication is thrombus formation [1]. In the systolic phase of the flow, excessive fluid stresses are generated by the non-physiologic flow patterns [2, 3]. In the closed valve position, a large pressure gradient is imposed across the device which leads to the generation of strong and damaging small-scale leakage flows that entrain platelets such that they are exposed to elevated stresses for excessive time durations [4–6].
Details
- Title: Subtitle
- Small Scale Flow Structure Evolution During Mechanical Heart Valve Closure
- Creators
- J Mousel - University of IowaH. S Udaykumar - University of IowaK. B Chandran - University of Iowa
- Resource Type
- Conference proceeding
- Publication Details
- Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, Vol.1
- Conference
- ASME 2013 Summer Bioengineering Conference, Sunriver, Oregon, USA, Jun. 26 - 29, 2013
- DOI
- 10.1115/SBC2013-14603
- Publisher
- American Society of Mechanical Engineers
- Language
- English
- Date published
- 06/26/2013
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Injury Prevention Research Center; Mechanical Engineering
- Record Identifier
- 9984196498002771
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