Conference proceeding
The intensity level reduction in radiation therapy
Proceedings of the 2005 ACM symposium on applied computing, Vol.1, pp.242-246
SAC '05
03/13/2005
DOI: 10.1145/1066677.1066736
Abstract
In this paper, we study an interesting intensity level reduction (ILR) problem, which is crucial for solving the "step-and-shoot" delivery planning problem in Intensity-Modulated Radiation Therapy (IMRT). IMRT aims to deliver a highly conformal radiation dose to a target tumor while sparing the surrounding normal tissues. Effective intensity level reduction approaches significantly reduce the patient's exposure under the radiation and improve the treatment efficiency. We propose a new intensity level reduction method for step-and-shoot delivery planning, and further model the intensity level reduction problem as computing a set of shortest monotone paths (SMPs) in certain specific geometric graphs, called multi-column graphs , of pseudo-polynomial sizes. Based on a judicious characterization of the intrinsic geometric structures of the graphs, we develop a novel graph pruning scheme and compute the SMPs without explicitly constructing the graphs, yielding an efficient O ( mn log n ) time algorithm for solving the intensity level reduction problem on an intensity map (specifying a radiation dose prescription) of size m x n.
Details
- Title: Subtitle
- The intensity level reduction in radiation therapy
- Creators
- Xiaodong Wu - University of Texas–Pan AmericanJohn Abraham - University of Texas–Pan American
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of the 2005 ACM symposium on applied computing, Vol.1, pp.242-246
- Series
- SAC '05
- DOI
- 10.1145/1066677.1066736
- Publisher
- ACM
- Language
- English
- Date published
- 03/13/2005
- Academic Unit
- Electrical and Computer Engineering; Radiation Oncology; The Iowa Institute for Biomedical Imaging
- Record Identifier
- 9984197335702771
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