Dataset
Characterizing Lipid Species in Metabolic Dysfunction-associated Steatotic Liver Disease in Persons with Type 1 Diabetes
figshare
06/02/2025
DOI: 10.6084/m9.figshare.29218382
Abstract
Although MASLD and lipid species have been extensively examined in persons with type 2 diabetes, much less is known in type 1 diabetes (T1D).We conducted a cross-sectional study of 30 participants with T1D, who were stratified as MASLD (cases) or controls, dependent on the results determined by FibroScan imaging. Fasting targeted lipidomics were measured in all participants. Our results suggest that persons with type 1 diabetes and MASLD have a higher BMI, are likely to be insulin resistant, and display elevated circulating levels of dihydroceramides, ceramides, diacylglycerols, and triacylglycerols, which are strongly associated with the pathogenesis of steatotic liver disease
Details
- Title: Subtitle
- Characterizing Lipid Species in Metabolic Dysfunction-associated Steatotic Liver Disease in Persons with Type 1 Diabetes
- Creators
- Adeyinka TaiwoHimani ThakkarJ. Alan MaschekJames CoxScott A SummersDiana JalalAyotunde DokunWilliam I. SivitzBhagirath Chaurasia
- Resource Type
- Dataset
- DOI
- 10.6084/m9.figshare.29218382
- Publisher
- figshare
- Language
- English
- Date published
- 06/02/2025
- Academic Unit
- Molecular Physiology and Biophysics; Fraternal Order of Eagles Diabetes Research Center; Nephrology; Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984829024502771
Metrics
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