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Dataset: Machine learning-assisted identification and quantification of hydroxylated metabolites of polychlorinated biphenyls in animal samples
Dataset   Open access

Dataset: Machine learning-assisted identification and quantification of hydroxylated metabolites of polychlorinated biphenyls in animal samples

Chunyun Zhang, Xueshu Li, Kimberly P Keil Stietz, Sunjay Sethi, Weizhu Yang, Rachel F Marek, Xinxin Ding, Pamela J Lein, Keri C Hornbuckle and Hans-Joachim Lehmler
University of Iowa
09/13/2022
DOI: 10.25820/data.006179
txt
Readme_OH-PCBs_MachineLearning12.76 kBDownloadView
README Describes files, methods, funding sources and personnel. Open Access Open Data Commons Attribution (ODC-By) V1.0
RData
D1_model-workspace-RRT861.87 kBDownloadView
Open Access Open Data Commons Attribution (ODC-By) V1.0
RData
D2_model-workspace-MSMS35.80 MBDownloadView
Open Access Open Data Commons Attribution (ODC-By) V1.0
R
D3_RRT-prediction-script1.42 kBDownloadView
Code/Script Open Access Open Data Commons Attribution (ODC-By) V1.0
R
D4_MSMS-prediction-script2.57 kBDownloadView
Code/Script Open Access Open Data Commons Attribution (ODC-By) V1.0

Abstract

This dataset includes the R workspaces, R scripts, and example data for predicting the relative retention times(RRT) and MS/MS data of methoxylated metabolites of polychlorinated biphenyls (MeO-PCBs) on a gas chromatography-tandem mass spectrometry (GC-MS/MS) system. In addition, molecular descriptors of 124 MeO-PCBs, including 99 cheminformatics-based descriptors and 6 substitution pattern-based descriptors, and the measured and predicted RRT and MS/MS data of 124 MeO-PCBs are provided in separate csv files.
Machine Learning OH-PCBs Hydroxylated PCBs Polychlorinated biphenyls GC-MS/MS Method Model Prediction Relative Retention Time Relative Response Factor PCB Metabolites Synthesis Core Analytical Core UC-Davis collaboration

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