Dataset
Dataset for 'Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves'
Digital Commons Data@Becker
06/25/2026
DOI: 10.17632/mv3crjbcsg.1
Abstract
This dataset contains quantitative summary data supporting the publication "Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves". The data include LC-MS/MS metabolomics measurements, in vitro axon degeneration assays, and in vivo histological and behavioral analyses used to generate the quantitative results presented in Figures 1–4 and Supplemental Figure S1. These data support the study's investigation of chronic SARM1 activation, phosphatidylserine dysregulation, macrophage activation, and the therapeutic effects of neuronal ABHD12 overexpression in a mouse model of sarmopathy.
Details
- Title: Subtitle
- Dataset for 'Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves'
- Creators
- Caitlin B. Dingwall - Washington University in St. LouisYo Sasaki - Washington University in St. LouisAmy Strickland - Washington University in St. LouisTong Wu - Washington University in St. LouisDaniel W. Summers - Washington University in St. LouisA. Joseph Bloom - Washington University in St. LouisAaron DiAntonio - Washington University in St. LouisJeffrey Milbrandt - Washington University in St. Louis
- Resource Type
- Dataset
- DOI
- 10.17632/mv3crjbcsg.1
- Publisher
- Digital Commons Data@Becker
- Grant note
- National Institute of Neurological Disorders and Stroke (https://ror.org/01s5ya894)
- Language
- English
- Date published
- 06/25/2026
- Academic Unit
- Iowa Neuroscience Institute; Biology
- Record Identifier
- 9985179093702771
Metrics
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