Dissertation
A CBCT investigation of morphological integration, cervical spine non-segmentation, and volumetric maxillary sinus association with dental impactions
University of Iowa
Doctor of Philosophy (PhD), University of Iowa
Summer 2022
DOI: 10.25820/etd.006737
Abstract
A deeper understanding of the craniofacial growth and development is an essential part of successful orthodontic treatment. The growth and development of craniofacial region is impacted by genetic, environmental, and interaction between genetic-environmental factors. Often times there is integration between different anatomical structures, and they influence each other during the ontogeny of craniofacial skeleton. Thus, there is a critical need to understand the role of these anatomical structures and how they might impact each other. Therefore, our aims in this study are: aim1: investigate whether there is developmental integration of the inferior alveolar nerve canal shape and the mandibular shape as well as the presence of asymmetry between right and left sides, aim2: investigate the prevalence and the morphology of cervical spine non-segmentation in CBCT scans taken for dental reasons, aim3: determine the association between impacted maxillary canines and premolars with the maxillary sinus and pharyngeal airway volumes. The study was conducted under The University of Iowa Institutional Review Board approval (#201601798). For all three aims, CBCT scans were retrieved from the archived database in the Department of Oral Pathology, Radiology, and Medicine the University of Iowa. For aim1, we selected 80 CBCT scans based on the following inclusion criteria: subject of 16 years old or older, no more than 6 missing teeth, interincisal distance ≤ 3 mm, no pathosis associated with the mandible, full head CBCT scans with no artifacts or obstructions in the field of view. For aim 2, we retrieved CBCT scans with known cases of non-segmentation using the following inclusion criteria: subjects aged ≥ 6 years, good imaging quality of CBCT scans, and non-syndromic patients. Aim 3, we selected 70 CBCT scans per study group (cases and controls) using the following inclusion criteria: patient aged ≥ 9 years, good imaging quality of CBCT scan, and a full head CBCT scan volume. Then, on the basis of eruption status of maxillary canine or premolar, we divided the selected CBCT scans into the following two groups: 1) the case group with an impacted tooth/tooth, and 2) the control group with normally erupted teeth. We used appropriate statistical tests to analyze the data. For aim1, we found that mandibular shape and IANC shape were strongly statistically significantly integrated (p < 0.001, rPLS=0.844); there was statistically significant (p<0.001) directional asymmetry in mandibular and IANC shape. Aim2, we found amongst the 110 CBCT (0.81%) scans with cervical spine non-segmentation 77.2% showed partial non-segmentation and 22.7% showed complete non-segmentation. For aim3, we found that the maxillary sinus volume in the impaction group is significantly smaller than one in the control group (p=0.048). While, no statistically significant difference between case group and control group in pharyngeal airway volume was identified.
Details
- Title: Subtitle
- A CBCT investigation of morphological integration, cervical spine non-segmentation, and volumetric maxillary sinus association with dental impactions
- Creators
- Daniah Mansour Alhazmi
- Contributors
- Shankar Rengasamy Venugopalan (Advisor)Trishul V Allareddy (Advisor)Xian Jin Xie (Committee Member)Huojun Cao (Committee Member)Sindhura Anamali (Committee Member)Siddharth R Vora (Committee Member)
- Resource Type
- Dissertation
- Degree Awarded
- Doctor of Philosophy (PhD), University of Iowa
- Degree in
- Oral Science
- Date degree season
- Summer 2022
- DOI
- 10.25820/etd.006737
- Publisher
- University of Iowa
- Number of pages
- x, 67 pages
- Copyright
- Copyright 2022 Daniah Mansour Alhazmi
- Language
- English
- Description illustrations
- Illustrations, charts, graphs, tables
- Description bibliographic
- Includes bibliographical references (pages 64-67).
- Public Abstract (ETD)
Dentists needs a good understanding of the growth of the skull, face and jaws in order to start treat their patients at the correct time. This knowledge includes knowing how the genetic and environmental factors could play a role on the growth of the jaws. The upper and lower jaws form separately and are surrounded by many other structures around them such as spinal column. Also, there are some structures embedded inside these jaws such as the nerve canal and the teeth. These structures may interact with each other and change the shape or the size of each other during the growth. Because of that, we are interested in this study to know: 1- if there is a shape interaction between the lower jaw and the nerve that supplies the jaw and teeth, 2- knowing what is the incidence of non-segmentation of bones of the spinal column, and 3- if the upper jaw sinus volume is smaller when the tooth is not erupted.
This study was conducted under the approved University of Iowa Institutional Review Board (#201601798). In order to conduct our study, for all the 3 aims, we collected dental CBCT images from The College of Dentistry and Dental Clinics at the University of Iowa based on specific inclusion/exclusion criteria. After that, we ran appropriate statistical tests to analyze the collected data for each aim. Interestingly, we found a strong interaction between the shape of the lower jaw and the shape of the inferior nerve canal (proxy for inferior alveolar neurovascular bundle), which indicates that the neurovascular bundle might play a role on establishing the shape of the lower jaw, as formation of the neurovascular bundle precedes lower jaw formation. Additionally, for the second study, we found that some of the bone of the cervical spinal column bones have an area of non-separation with an incidence around 0.81% in our repository of CBCT images. Furthermore, our result shows that the maxillary sinus is smaller in volume when teeth are not erupted compared to maxillary sinus when teeth are erupted.
- Academic Unit
- Oral Pathology, Radiology and Medicine; Craniofacial Anomalies Research Center
- Record Identifier
- 9984285452502771
Metrics
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