Background Student registered nurse anesthetists (SRNAs) face challenging didactic content and rigorous clinical requirements throughout their curriculum that can have an impact on their mental wellness resulting in stress and anxiety. Purpose The purpose of this project was to provide mental wellness resources and education to SRNAs at a Midwest nurse anesthesia program in the form of a mobile application. Methods Institutional review board approval was obtained for the assessment of stress and anxiety levels in SRNAs. Recruitment was completed via email and consent was obtained when the students submitted an anonymous baseline perceived stress and anxiety assessment. The SRNAs were then offered a mobile wellness application for download. Perceived stress and anxiety were reassessed at one-month intervals beginning in October 2023 and ending in January 2024. Findings The findings of this project revealed that there was a linear decrease in perceived stress levels from the baseline to the fourth post-intervention assessment. Using a paired t-test, there was a statistically significant decrease in perceived stress levels at the fourth post-intervention assessment (p = 0.026). The anxiety results did not show a statistically significant change. Increased application use was associated with decreased stress and anxiety scores. However, there was not a statistically significant correlation between application use and stress or anxiety scores. Discussion This project demonstrated that SRNAs at this Midwest academic institution experience moderate levels of stress and anxiety on average. It was also shown that wellness training can have a positive impact on stress and anxiety levels.