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Background: Intracranial hemorrhagic strokes secondary to cerebral amyloid angiopathy (CAA) are associated with multisystem complications and high rates of mortality. The purpose of this case report is to highlight the challenges associated with restoring functional mobility in the acute stage of treatment after intracranial hemorrhage (ICH) secondary to CAA. Case Description: An 83-year-old female suffered an ICH secondary to CAA. The patient presented with severe strength, balance, and functional mobility deficits as well as global aphasia. Intervention: The physical therapists involved in her care initiated early mobilization consisting of purposeful positioning, functional strengthening, and pre-gait training to prevent deleterious effects of immobility. Discussion: The patient’s care was complicated by multiple adverse events and ultimately, she did not recover from the neurological insult. However, the case provided examples of challenges and benefits of early mobilization following ICH. Additionally, the case confirmed that early mobilization can be carried out safely in the acute neurological care setting.