Background: In the United States there are 21 million general anesthetics performed each year with roughly 210,000 airway emergencies. Airway emergencies are infrequent crises events that, if not handled effectively and efficiently, can lead to devastating outcomes. Simulation training has the potential to bridge knowledge gaps for infrequently used skills and new nursing staff. Purpose: To improve nursing management of postoperative airway emergencies in the Ambulatory Surgery Center (ASC) Postoperative Anesthesia Unit (PACU). The aim of the project was to design a mastery checklist and pre/post simulation survey, improve knowledge of airway crises event, and improve confidence with airway crises events. Methods: This project followed the Iowa Model and Implementation Framework. A hospital wide needs assessment was conducted in the summer of 2023, that identified simulation as the desired format for ASC PACU education. A pre/post simulation survey and mastery checklist were created utilizing a Modified Delphi process with anesthesia faculty. Emergency airway simulations were run in the fall of 2023 and winter of 2024 for ASC PACU nurses. Data from the survey and checklist was collected and complied after each simulation session. Findings: There was roughly a 20% improvement in all categories, comparing the pre and post simulation surveys addressing comfort/confidence and efficiency. Initially, the mastery checklist had zero passing participants, but with remediation, there was 100% pass rate for the 24 participants. Discussion: The utilization airway emergency simulation has improved ASC PACU nurses’ comfort/confidence and efficiency. This simulation has become an annual competency for the ASC PACU nursing staff in this institution and all participants have demonstrated competency. At the publishing of this paper there have been zero airway emergencies within this institution.