This dissertation explores the sensory designs of natural and artificial grottoes (cave-like spaces with flowing water) found in Roman villas across Italy from the second century BCE to the second century CE. These grottoes were carefully designed with water displays, architectural features, paintings, mosaics, and sculptures that engaged bodily senses beyond sight. This study traces the development of these monuments, focusing on four case studies that illustrate pivotal moments in residential grotto design, their associated sensory experiences, and how these experiences dovetail with the overall villa visit. Using 3D digital modeling, this dissertation recreates varying light levels and water in these four grottoes to reconstruct their immersive qualities beyond what remains in archaeological evidence. The dissertation consists of five body chapters, the first of which surveys the material remains of the 41 extant ancient Roman villa grottoes in Italy. The subsequent chapters examine four case studies, which are the artificial grotto of Maecenas in Rome, the natural cave at Sperlonga, the elaborate water features of Villa San Marco in Stabiae, and the dining grotto and canal at Emperor Hadrian's villa in Tivoli. By combining archaeological analysis with digital reconstruction, this dissertation offers modern audiences a deeper understanding of how ancient Romans engaged with art and architecture in their domestic spaces. It further provides valuable insights into the lived experiences of individuals in the ancient world, enriching the appreciation of Roman history and cultural heritage.