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Background: Prolonged symptoms following a concussion, known as post-concussion syndrome (PCS) is beginning to gain relevance in recent literature. There is some evidence indicating the adverse effects of PCS on a patient’s life, the evaluation of PCS, and the treatment of PCS. Purpose: The purpose of this case study is to provide examples of interventions and progressions used to successfully treat a patient experiencing symptoms related to PCS following a mild traumatic brain injury (mTBI). Case Description: A 55-year-old male referred to therapy 2-weeks after experiencing a diagnosed mTBI. His pertinent medical history included 4 diagnosed mTBI in the past. He was experiencing symptoms including a constant headache, increased cervical stiffness and pain, dizziness, increased frustration, difficulty sleeping, and impaired balance and lower extremity coordination. Interventions: He received 14 physical therapy sessions over an eight-week period, while also receiving speech therapy. The physical therapy interventions included manual therapy and postural strengthening, vestibular and oculomotor training, balance interventions, and work simulated tasks. Outcomes: The patient was evaluated using certain parts of the vestibular/ocular motor screening (VOMS) exam as well as the concussion balance test (COBALT). The patient returned to his previous level of employment indicating an improvement in overall function. His reported pain levels decreased from 6/10 upon evaluation to 0/10 on the final day of therapy. Discussion: Throughout his episode of care, he demonstrated improvements in cervical stiffness and pain, lower extremity coordination, balance, and a large reduction in his experienced headache and dizziness. This case report outlines the interventions used in a specific patient aimed to resolve the experienced symptoms presumably due to PCS.