Objective: To assess neck angulation and endograft oversizing as factors contributing to folding. Endograft folding will then be assessed on its role in endograft fixation strength. Methods: Bench top flow loop experiments were performed with barbless Gore Excluder endovascular grafts (EVG) that were deployed into silicone aorta-AAA models with neck angles of 0, 30, and 60. A total of five oversizings were tested: -7%, 2%, 12%, 24%, and 38% with N= 3 for each oversizing at each neck angle for a total of 45 experiments. Photographs of the stent apex to apex distances were taken for the entire circumference of the device for a total of 8 photos per experiment. Measurements of the apex to apex distance were taken for the top three stent layers and variance for each stent layer was calculated. Variances for all three stent layers were summed to represent the folding metric. The silicone model was then removed from the flow loop and placed on the uniaxial extension tester to for pull out testing to assess impact on attachment strength. Results: Neck angle and oversizing increases folding risk at oversizing ≥12% for 0° and 30° neck angles, and ≥ 2% oversizing for a 60° neck angle. Folding metric comparison between 0° vs. 30° and 0° vs. 60° across all oversizings had statistical significance (Mann-Whitney U, p
Dissertation
Role of neck angulation and endograft oversizing in folding and its impact on device fixation strength
University of Iowa
Doctor of Philosophy (PhD), University of Iowa
Spring 2012
DOI: 10.17077/etd.l8ngw3f2
Free to read and download, Open Access
Abstract
Details
- Title: Subtitle
- Role of neck angulation and endograft oversizing in folding and its impact on device fixation strength
- Creators
- Kathleen Kei Lin - University of Iowa
- Contributors
- Madhavan L. Raghavan (Advisor)Krishnan B. Chandran (Committee Member)Sarah Vigmostad (Committee Member)Jia Lu (Committee Member)Jafar Golzarian (Committee Member)
- Resource Type
- Dissertation
- Degree Awarded
- Doctor of Philosophy (PhD), University of Iowa
- Degree in
- Biomedical Engineering
- Date degree season
- Spring 2012
- Publisher
- University of Iowa
- DOI
- 10.17077/etd.l8ngw3f2
- Number of pages
- x, 109 pages
- Copyright
- Copyright 2012 Kathleen Lin
- Language
- English
- Description bibliographic
- Includes bibliographical references (pages 105-109).
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9983776918202771
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