Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine

Ted M Burns; Gordon A Smith; Jeffrey A Allen; Anthony A Amato; W David Arnold; Richard Barohn; Michael Benatar; Shawn J Bird; Mark Bromberg; Nizar Chahin; Emma Ciafaloni; Jeffrey A Cohen; Andrea Corse; Brian A Crum; William S David; Elliot Dimberg; Eduardo A De Sousa; Peter D Donofrio; P James B Dyck; Andrew G Engel; Erik R Ensrud; Mark Ferrante; Miriam Freimer; Karissa L Gable; Summer Gibson; James M Gilchrist; Jonathan M Goldstein; Clifton L Gooch; Brent P Goodman; Dmitri Gorelov; Sidney M Gospe Jr; Namita A Goyal; Amanda C Guidon; Jeffrey T Guptill; Laurie Gutmann; Ludwig Gutmann; Kelly Gwathmey; Yadollah Harati; C Michel Harper Jr; Michael K Hehir; Lisa D Hobson-Webb; James F Howard Jr; Carlayne E Jackson; Nicholas Johnson; Sarah M Jones; Vern C Juel; Henry J Kaminski; Chafic Karam; Kathleen D Kennelly; Sami Khella; Julie Khoury; John C Kincaid; John T Kissel; Noah Kolb; David Lacomis; Shafeeq Ladha; Daniel Larriviere; Richard A Lewis; Yuebing Li; William J Litchy; Eric Logigian; Jau-Shin Lou; Daniel J L MacGowen; Ricardo Maselli; Janice M Massey; Michelle L Mauermann; Katherine D Mathews; Matthew N Meriggioli; Robert G Miller; Joon-Shik Moon; Tahseen Mozaffar; Sharon P Nations; Richard J Nowak; Lyle W Ostrow; Robert M Pascuzzi; Amanda Peltier; Katherine Ruzhansky; David P Richman; Mark A Ross; Devon I Rubin; James A Russell; George M Sachs; Mohammad Kian Salajegheh; David S Saperstein; Stephen Scelsa; Duygu Selcen; Aziz Shaibani; Perry B Shieh; Nicholas J Silvestri; J Rob Singleton; Benn E Smith; Yuen T So; Guillermo Solorzano; Eric J Sorenson; Jayashri Srinivasen; Jinny Tavee; Rabi Tawil; Pariwat Thaisetthawatkul; Charles Thornton; Jaya Trivedi; Steven Vernino; Annabel K Wang; Tyler A Webb; Michael D Weiss; Anthony J Windebank; Gil I Wolfe

doi:10.1002/mus.25009

Editorial

Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine

Ted M Burns, Gordon A Smith, Jeffrey A Allen, Anthony A Amato, W David Arnold, Richard Barohn, Michael Benatar, Shawn J Bird, Mark Bromberg, Nizar Chahin, …

Muscle & nerve, Vol.53(2), pp.165-168

02/2016

DOI: 10.1002/mus.25009

PMID: 26662952

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Abstract

Neuromuscular Junction Diseases - drug therapy

Humans

4-Aminopyridine - therapeutic use

4-Aminopyridine - analogs & derivatives

Orphan Drug Production - economics

Orphan Drug Production - methods

Potassium Channel Blockers - therapeutic use

Physicians - psychology

Neuromuscular Junction Diseases - economics

Details

Title: Subtitle: Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine
Creators: Ted M Burns - Department of Neurology, University of Virginia, Charlottesville, Virginia, 22908, USA
Gordon A Smith - Department of Neurology University of Utah, Salt Lake City, Utah, USA
Jeffrey A Allen - Department of Neurology, University of Minnesota, Minneapolis, Minnesota, USA
Anthony A Amato - Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
W David Arnold - Department of Neurology and Physical Medicine and Rehabilitation, Ohio State University, Columbus, Ohio, USA
Richard Barohn - Department of Neurology, University of Kansas, Kansas City, Kansas, USA
Michael Benatar - Department of Neurology, University of Miami, Miami, Florida, USA
Shawn J Bird - Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Mark Bromberg - Department of Neurology University of Utah, Salt Lake City, Utah, USA
Nizar Chahin - Department of Neurology, University of Connecticut, Farmington, Connecticut, USA
Emma Ciafaloni - Department of Neurology, University of Rochester, Rochester, New York, USA
Jeffrey A Cohen - Department of Neurology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA
Andrea Corse - Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Brian A Crum - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
William S David - Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Elliot Dimberg - Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Eduardo A De Sousa - Department of Neurology, University of Oklahoma, Oklahoma City, Oklahoma, USA
Peter D Donofrio - Department of Neurology, Vanderbilt University, Nashville, Tennessee, USA
P James B Dyck - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Andrew G Engel - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Erik R Ensrud - Department of Neurology, Boston Veterans Affairs, Boston, Massachusetts, USA
Mark Ferrante - Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Miriam Freimer - Department of Neurology, Ohio State University, Columbus, Ohio, USA
Karissa L Gable - Department of Neurology, Duke University, Durham, North Carolina, USA
Summer Gibson - Department of Neurology University of Utah, Salt Lake City, Utah, USA
James M Gilchrist - Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA
Jonathan M Goldstein - Department of Neurology, Hospital for Special Surgery, New York, New York, USA
Clifton L Gooch - Department of Neurology, University of South Florida, Tampa, Florida, USA
Brent P Goodman - Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
Dmitri Gorelov - Crystal Run Healthcare, Middletown, New York, USA
Sidney M Gospe Jr - Department of Neurology, University of Washington, Seattle, Washington, USA
Namita A Goyal - Department of Neurology, University of California Irvine, Irvine, California, USA
Amanda C Guidon - Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Jeffrey T Guptill - Department of Neurology, Duke University, Durham, North Carolina, USA
Laurie Gutmann - Division of Neurology, University of Iowa, Iowa City, Iowa, USA
Ludwig Gutmann - Division of Neurology, University of Iowa, Iowa City, Iowa, USA
Kelly Gwathmey - Department of Neurology, University of Virginia, Charlottesville, Virginia, 22908, USA
Yadollah Harati - Department of Neurology, Baylor College of Medicine, Houston, Texas, USA
C Michel Harper Jr - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Michael K Hehir - Department of Neurology, University of Vermont, Burlington, Vermont, USA
Lisa D Hobson-Webb - Department of Neurology, Duke University, Durham, North Carolina, USA
James F Howard Jr - Department of Neurology, University of North Carolina, Chapel Hill, North Carolina, USA
Carlayne E Jackson - Department of Neurology and Otolaryngology, University of Texas Health Science Center, San Antonio, Texas, USA
Nicholas Johnson - Department of Neurology University of Utah, Salt Lake City, Utah, USA
Sarah M Jones - Department of Neurology, University of Virginia, Charlottesville, Virginia, 22908, USA
Vern C Juel - Department of Neurology, Duke University, Durham, North Carolina, USA
Henry J Kaminski - Department of Neurology, George Washington University, Washington, DC, USA
Chafic Karam - Department of Neurology, University of North Carolina, Chapel Hill, North Carolina, USA
Kathleen D Kennelly - Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Sami Khella - Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Julie Khoury - Department of Neurology, Oregon Health Science University, Portland, Oregon, USA
John C Kincaid - Department of Neurology, Indiana University, Indianapolis, Indiana, USA
John T Kissel - Department of Neurology, Ohio State University, Columbus, Ohio, USA
Noah Kolb - Department of Neurology University of Utah, Salt Lake City, Utah, USA
David Lacomis - Department of Neurology and Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Shafeeq Ladha - Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA
Daniel Larriviere - Department of Neurology, Ochsner Neuroscience Institute, New Orleans, Louisiana, USA
Richard A Lewis - Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA
Yuebing Li - Department of Neurology, Cleveland Clinic, Cleveland, Ohio, USA
William J Litchy - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Eric Logigian - Department of Neurology, University of Rochester, Rochester, New York, USA
Jau-Shin Lou - Department of Neurology, University of North Dakota, Sanford Health, Fargo, North Dakota, USA
Daniel J L MacGowen - Department of Neurology, Department of Neurology, Mount Sinai Beth Israel Hospital, New York, New York, USA
Ricardo Maselli - Department of Neurology, University of California, Davis, Sacramento, California, USA
Janice M Massey - Department of Neurology, Duke University, Durham, North Carolina, USA
Michelle L Mauermann - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Katherine D Mathews - Division of Neurology, University of Iowa, Iowa City, Iowa, USA
Matthew N Meriggioli - Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
Robert G Miller - Department of Neurosciences, California Pacific Medical Center, San Francisco, California, USA
Joon-Shik Moon - Department of Neurology, University of Oklahoma, Oklahoma City, Oklahoma, USA
Tahseen Mozaffar - Department of Neurology, University of California Irvine, Irvine, California, USA
Sharon P Nations - Department of Neurology and Neurotherapeutics, University Texas Southwestern, Dallas, Texas, USA
Richard J Nowak - Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA
Lyle W Ostrow - Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Robert M Pascuzzi - Department of Neurology, Indiana University, Indianapolis, Indiana, USA
Amanda Peltier - Department of Neurology, Vanderbilt University, Nashville, Tennessee, USA
Katherine Ruzhansky - Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA
David P Richman - Department of Neurology, University of California, Davis, Sacramento, California, USA
Mark A Ross - Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
Devon I Rubin - Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
James A Russell - Department of Neurology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA
George M Sachs - Department of Neurology, Alpert Medical School of Brown University, Providence, Rhode Island, USA
Mohammad Kian Salajegheh - Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
David S Saperstein - Phoenix Neurological Associates, Phoenix, Arizona, USA
Stephen Scelsa - Department of Neurology, Department of Neurology, Mount Sinai Beth Israel Hospital, New York, New York, USA
Duygu Selcen - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Aziz Shaibani - Nerve and Muscle Center of Texas, Houston, Texas, USA
Perry B Shieh - Department of Neurology, University of California at Los Angeles, Los Angeles, California, USA
Nicholas J Silvestri - Department of Neurology, University of Buffalo, Buffalo, New York, USA
J Rob Singleton - Department of Neurology University of Utah, Salt Lake City, Utah, USA
Benn E Smith - Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
Yuen T So - Department of Neurology, Stanford University, Palo Alto, California, USA
Guillermo Solorzano - Department of Neurology, University of Virginia, Charlottesville, Virginia, 22908, USA
Eric J Sorenson - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Jayashri Srinivasen - Department of Neurology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA
Jinny Tavee - Department of Neurology, Cleveland Clinic, Cleveland, Ohio, USA
Rabi Tawil - Department of Neurology, University of Rochester, Rochester, New York, USA
Pariwat Thaisetthawatkul - Department of Neurology, University of Nebraska, Omaha, Nebraska, USA
Charles Thornton - Department of Neurology, University of Rochester, Rochester, New York, USA
Jaya Trivedi - Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA
Steven Vernino - Department of Neurology and Neurotherapeutics, University Texas Southwestern, Dallas, Texas, USA
Annabel K Wang - Department of Neurology, Veterans Affairs Long Beach Healthcare System, Long Beach, California, USA
Tyler A Webb - Department of Neurology, University of Oklahoma, Oklahoma City, Oklahoma, USA
Michael D Weiss - Department of Neurology, University of Washington, Seattle, Washington, USA
Anthony J Windebank - Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Gil I Wolfe - Department of Neurology, University of Buffalo, Buffalo, New York, USA
Resource Type: Editorial
Publication Details: Muscle & nerve, Vol.53(2), pp.165-168
Publisher: United States
DOI: 10.1002/mus.25009
PMID: 26662952
ISSN: 0148-639X
eISSN: 1097-4598
Language: English
Date published: 02/2016
Academic Unit: Neurology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurology (Pediatrics)
Record Identifier: 9984013278202771

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