Poster
Bis(monoacylglycerol) phosphate levels are elevated at baseline in carriers of pathogenic variants in LRRK2 and GBA1 and do not predict progression of PD in PPMI cohorts
Zenodo
07/31/2022
DOI: 10.5281/zenodo.7004952
Abstract
Urine Bis(monoacylglcerol) phosphate (BMP) has been identified as a biomarker that identifies carriers variants in the LRRK2 gene. The purpose of this study was to investigate BMP in patients with LRRK2-associated Parkinson's disease in a longitudinal study. We found that BMP was elevated in patients with LRRK2 PD compared to sporadic PD. We did not identify phenotypic variation associated with LRRK2.
Details
- Title: Subtitle
- Bis(monoacylglycerol) phosphate levels are elevated at baseline in carriers of pathogenic variants in LRRK2 and GBA1 and do not predict progression of PD in PPMI cohorts
- Creators
- Kalpana M. MerchantTanya SimuniJanel FedlerChelsea Caspell-GarciaMichael BrummKelly NudelmanElizabeth TengstrandtFrank HsiehRoy N. AlcalayChristopher CoffeyLana ChahineTatiana ForoudAndrew SingletonTodd ShererAndrew SiderowfCaroline TannerKen Marek
- Resource Type
- Poster
- DOI
- 10.5281/zenodo.7004952
- Publisher
- Zenodo
- Language
- English
- Date published
- 07/31/2022
- Academic Unit
- Biostatistics
- Record Identifier
- 9984530365402771
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