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Thesis
The efficacy of 37% phosphoric acid + Mi Paste Plus on remineralization of enamel white spot lesions
University of Iowa
Master of Science (MS), University of Iowa
Spring 2011
DOI: 10.17077/etd.hdfq3if3
Abstract
<p><strong>Purpose:</strong> This <em>in vitro</em> study evaluated the effectiveness of using a 37% phosphoric acid liquid etchant along with MI Paste Plus™ powered technology compared to using MI Paste Plus™ alone or to an artificially created saliva solution in decreasing the demineralization and enhancing the remineralization of artificial carious lesions created on extracted human teeth. The teeth were analyzed and compared using polarized light microscopy, quantitative light-induced fluorescence, and digital photography.</p>
<p><strong>Materials and Methods:</strong> One hundred three recently extracted non-carious human third molar teeth without observable white-spot lesions, decalcification, or dental fluorosis were selected for this twelve day study and randomly divided into four treatment groups as follows:</p>
<p>Group 1 (Control) - Artificial saliva solution (27 teeth)</p>
<p>Group 2 (MIP) - MI Paste Plus™ application for 30 minutes daily for 12 days (26 teeth)</p>
<p>Group 3 (15MIP) - 15 second etch every third day and MI Paste Plus™ application for 30 minutes daily for 12 days (25 teeth)</p>
<p>Group 4 (1MIP) - 1 minute etch on day one ONLY and application of MI Paste Plus™ for 30 minutes daily for 12 days (25 teeth).</p>
<p><strong>Results:</strong> Results of one<–>way ANOVA revealed there was a significant effect for the type of treatment on the lesion depth (p = 0.0027). The post-hoc Tukey-Kramer's test indicated there was a statistically significant difference between the two groups (15MIP and 1MIP) that incorporated an acid etch in combination with MI Paste Plus™ and the group with exposure to MI Paste Plus™ alone (MIP). In addition, results of one<–>way ANOVA showed that there was no statistically significant effect for type of treatment on the change in fluorescence (p = 0.1417) or the change in density (p = 0.1934).</p>
<p><strong>Conclusions:</strong> The results of the present study revealed there was a significant effect for the type of treatment on the lesion depth (p = 0.0027). However, the only significant difference found was between the two groups (15MIP and 1MIP) that incorporated an acid etch in combination with MI Paste Plus™ and the group with exposure to MI Paste Plus™ alone (MIP). Thus, daily applications of MI Paste Plus™, with or without an acid etch, did not produce a statistically significant difference in mean lesion depth when compared to the control (artificial saliva group). In addition, the results of the present study showed that there was no statistically significant effect for type of treatment on the change in fluorescence (p = 0.1417) or the change in density (p = 0.1934). Further research is needed to evaluate MI Paste Plus™ capability in prevention of demineralization and/or enhancement of remineralization by conducting randomized clinical trials.</p>
Details
- Title: Subtitle
- The efficacy of 37% phosphoric acid + Mi Paste Plus on remineralization of enamel white spot lesions
- Creators
- Kristin Dumboski Clark - University of Iowa
- Contributors
- Robert N. Staley (Advisor)James Wefel (Committee Member)Clayton Parks (Committee Member)Fang Qian (Committee Member)
- Resource Type
- Thesis
- Degree Awarded
- Master of Science (MS), University of Iowa
- Degree in
- Orthodontics
- Date degree season
- Spring 2011
- Publisher
- University of Iowa
- DOI
- 10.17077/etd.hdfq3if3
- Number of pages
- viii, 78 pages
- Copyright
- Copyright © 2011 Kristin Dumboski Clark
- Comment
This thesis has been optimized for improved web viewing. If you require the original version, contact the University Archives at the University of Iowa: https://www.lib.uiowa.edu/sc/contact/.
- Language
- English
- Description bibliographic
- Includes bibliographical references (pages 72-78).
- Academic Unit
- Orthodontics
- Record Identifier
- 9983777088502771
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