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1,5-Polyols: Challenging motifs for configurational assignment and synthesis
Journal article   Peer reviewed

1,5-Polyols: Challenging motifs for configurational assignment and synthesis

Gregory K Friestad and Gopeekrishnan Sreenilayam
Pure and Applied Chemistry, Vol.83(3), pp.461-478
01/31/2011
DOI: 10.1351/PAC-CON-10-10-19

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Abstract

Despite the well-established methods for stereochemical assignments and synthesis of 1,3-diols, the corresponding 1,5-diols and -polyols present specific challenges which remain unsolved. This article highlights some new strategies and methodologies specifically designed for the 1,5-diol motif.
natural products alcohols asymmetric synthesis polyketides coupling reactions

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