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17O-decoupled 1H detection using a double-tuned coil
Journal article   Open access   Peer reviewed

17O-decoupled 1H detection using a double-tuned coil

Ravinder Reddy, Alan H Stolpen, Sridhar R Charagundla, E.K Insko and John S Leigh
Magnetic resonance imaging, Vol.14(9), pp.1073-1078
1996
DOI: 10.1016/S0730-725X(96)00227-5
PMID: 9070998
url
https://doi.org/10.1016/S0730-725X(96)00227-5View
Published (Version of record) Open Access

Abstract

17O-decoupled proton MR spectroscopy and imaging with a double-tuned radiofrequency (RF) coil at 2 T was used to detect and quantify H 2 17O in tissue phantoms containing various concentrations of 17O-enriched water in 5% gelatin. The pulse sequence used in these experiments consisted of a conventional proton spinecho sequence with RF irradiation at the 17O resonance frequency applied between the proton 90° pulse and the signal acquisition window. The double-tuned coil provided several advantages over systems using separate RF coils for 17O decoupling and proton excitation/detection, including ensuring that the same (or similar) sample volumes are excited and decoupled and permitting accurate calibration of the 17O decoupling pulse amplitude. The efficiency of 17O decoupling as a function of decoupling RF amplitude, decoupling duration, and decoupling resonance offset was investigated. Finally, the specific absorption rate of the 17O decoupled pulse sequence was investigated and found to lie within federal guidelines at 1.5 T.
Proton NMR 17O Decoupling Gelatin Double-tuned coil

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