Journal article
[18F]FDG PET/CT: EANM procedure guidelines for tumour imaging: version 3.0
The EANM Journal, Vol.1, 100006
12/2025
DOI: 10.1016/j.eanmj.2025.100006
Abstract
The purpose of these guidelines is to assist physicians in recommending, performing, interpreting and reporting the results of [18F]FDG PET/CT for oncological imaging of adult and paediatric patients. PET is a quantitative imaging technique and therefore requires a common quality control (QC)/quality assurance (QA) procedure to maintain the accuracy and precision of quantitation. Repeatability and reproducibility are two essential requirements for any quantitative measurement and/or imaging biomarker. Repeatability relates to the uncertainty in obtaining the same result in the same patient when they are examined more than once on the same system. However, imaging biomarkers should also have adequate reproducibility, i.e. the ability to yield the same result in the same patient when that patient is examined on different systems and at different imaging sites. Adequate repeatability and reproducibility are essential for the clinical management of patients and the use of [18F]FDG PET/CT within multicentre trials. A common standardised imaging procedure will help promote the appropriate use of [18F]FDG PET/CT imaging and increase the value of publications and, therefore, their contribution to evidence-based medicine. Moreover, consistency in numerical values between platforms and imaging centres that acquire the data will potentially enhance the role of semi-quantitative and quantitative image interpretation. Precision and accuracy are additionally important as [18F]FDG PET/CT is used to evaluate tumour response as well as for diagnosis, prognosis and staging. Therefore, both the previous and these new guidelines specifically aim to achieve standardised uptake value harmonisation in multicentre settings.
Details
- Title: Subtitle
- [18F]FDG PET/CT: EANM procedure guidelines for tumour imaging: version 3.0
- Creators
- Ronald Boellaard - Amsterdam University Medical CentersKen Herrmann - Essen University HospitalSally F. Barrington - King's College LondonIain Cranston - Portsmouth Hospitals NHS TrustFelix M. Mottaghy - RWTH Aachen UniversityCorneline J. Hoekstra - Jeroen Bosch ZiekenhuisThomas Beyer - Medical University of ViennaLucy RG Pike - Nuclear Medicine, Mid and South Essex NHS Foundation Trust, Essex, United KingdomAntoon TM Willemsen - University Medical Center GroningenMichael M. Graham - Department of Radiology, University of Iowa, Iowa City, USAJosée M. Zijlstra - Amsterdam University Medical CentersFred Verzijlbergen - Radboud University Medical CenterBernd J. Krause - University of RostockAlbert J. Arends - Catharina ZiekenhuisWolfgang A. Weber - Technical University of MunichOtto S. Hoekstra - Amsterdam University Medical CentersRoberto C. Delgado Bolton - Hospital San PedroGiorgio Testanera - King's College LondonFrancesco Giammarille - International Atomic Energy AgencySigrid Stroobants - Antwerp University HospitalChristophe Deroose - Universitair Ziekenhuis LeuvenArturo Chiti - Vita-Salute San Raffaele UniversityWim JG Oyen - Rijnstate Hospital
- Resource Type
- Journal article
- Publication Details
- The EANM Journal, Vol.1, 100006
- DOI
- 10.1016/j.eanmj.2025.100006
- ISSN
- 3051-2921
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 12/2025
- Academic Unit
- Radiology; Radiation Oncology
- Record Identifier
- 9984969244702771
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