Journal article
(2'S,3'S,4'R)-5'-O-benzoyl-3'-deoxy-3'β-diethylphosphono-2'-O-tert-butyldimethylsilyluridine
Acta crystallographica. Section C, Crystal structure communications, Vol.52(6), pp.1552-1554
1996
DOI: 10.1107/S0108270195014831
PMID: 8766898
Abstract
3′-Hydroxy-3′-diethylphosphononucleosides readily undergo radical deoxygenation under modified Barton conditions to give two diastereomers of the parent diethyl phosphonate. However, the stereochemistry of the diastereomers is difficult to establish by spectral means. When the major product of one such reaction was obtained in crystalline form, a single crystal diffraction analysis was conducted on that diastereomer, the title compound, C26H39N2O9PSi.
Details
- Title: Subtitle
- (2'S,3'S,4'R)-5'-O-benzoyl-3'-deoxy-3'β-diethylphosphono-2'-O-tert-butyldimethylsilyluridine
- Creators
- Wenkui Lan Mceldoon - Department of Chemistry, University of Iowa, Iowa City, IA 52242, United StatesDale C Swenson - Department of Chemistry, University of Iowa, Iowa City, IA 52242, United StatesDavid F Wiemer - Department of Chemistry, University of Iowa, Iowa City, IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- Acta crystallographica. Section C, Crystal structure communications, Vol.52(6), pp.1552-1554
- Publisher
- Blackwell
- DOI
- 10.1107/S0108270195014831
- PMID
- 8766898
- ISSN
- 0108-2701
- eISSN
- 1600-5759
- Language
- English
- Date published
- 1996
- Academic Unit
- Neuroscience and Pharmacology; Chemistry
- Record Identifier
- 9984216561902771
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