Journal article
30-Month performance of a 10-MDP based universal adhesive system under mechanical and biological perspectives
International journal of adhesion and adhesives, Vol.136, 103869
01/2025
DOI: 10.1016/j.ijadhadh.2024.103869
Abstract
Strategies towards the long-term durability of dentin-adhesive interface is the goal of many investigations. As the universal dentin bonding systems (DBS) represents a promissory category, other approaches seem to be refrained. Besides their chemical capacity to bond to dentin, their ability in terms of suppression of dentin metalloproteinases of matrix at the interface is unclear. This study aimed to evaluate the long-term adhesive performance and gelatinolytic activity effect of a 10-MDP-based universal DBS compared with 2 % chlorhexidine digluconate (CHX) as control to connect the understanding of mechanical and biological mechanisms. For this, bond strength to dentin (μTBS) and in situ zymography (Z) at initial, 6-month, and 30-month aging times were run. 102 sound human molars were randomized according to DBS: Adper Single Bond 2 – (SB - MDP-free control); Adper Single Bond Universal in etch-and-rinse (SUER) and self-etching (SUSE) modes. They were subdivided according to dentin pretreatment: W- water or CHX-2% (30s-passive application). The specimens were restored according to the manufacturer's instructions. For μTBS (n = 12), beams (0.64 mm2) were obtained and tested (500N/0.5 mm/min). For Z (n = 5), 0.1 mm-thick slices were incubated with fluorescein-conjugated gelatin (24h/37 °C) and analyzed by confocal laser scanning microscopy. Data were analyzed by three-way ANOVA and Tukey's test (p < 0.05). At 6-month, CHX effectiveness was observed in some circumstances under both tests. However, 30-month assessments evidenced no difference neither among the groups regardless of DBSs nor pretreatment for all comparisons, despite some peculiarities detected under Z. It is concluded that the 10-MDP universal DBS present limited action over the proteolytic action.
•10-MDP universal system was not superior regarding bond strength over 30 months.•6-month gelatinolytic inhibition by universal systems was not promissory as CHX.•The use of CHX was effective regardless the combination to any tested system.•After 30 months, all bonding systems performed similarly associated with or not CHX.
Details
- Title: Subtitle
- 30-Month performance of a 10-MDP based universal adhesive system under mechanical and biological perspectives
- Creators
- Marina Ciccone Giacomini - Universidade de São PauloLinda Wang - Universidade de São PauloGiovanna Speranza Zabeu - Universidade de São PauloPolliana Mendes Candia Scaffa - Oregon Health & Science UniversityCristina De Mattos Pimenta Vidal - Department of Operative Dentistry, College of Dentistry, University of Iowa, 801 Newton Rd, Iowa City, IA 52242, USAMylena Proença Costa - Universidade de São Paulo
- Resource Type
- Journal article
- Publication Details
- International journal of adhesion and adhesives, Vol.136, 103869
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.ijadhadh.2024.103869
- ISSN
- 0143-7496
- eISSN
- 1879-0127
- Grant note
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brasil (CAPES): 001 Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq: 163402/2015-9, 408865/2016-4
This study was performed by MCG as fulfillment of her phD's degree at the University of Sao Paulo, Brasil. The authors are grateful to Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brasil (CAPES) - Finance Code 001 and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq (163402/2015-9 and 408865/2016-4) for the financial support
- Language
- English
- Date published
- 01/2025
- Academic Unit
- Operative Dentistry
- Record Identifier
- 9984745357402771
Metrics
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