Journal article
A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data
Environmental health perspectives, Vol.131(6), 065001
06/23/2023
DOI: 10.1289/EHP11484
PMCID: PMC10289218
PMID: 37352010
Abstract
Funding agencies, publishers, and other stakeholders are pushing environmental health science investigators to improve data sharing; to promote the findable, accessible, interoperable, and reusable (FAIR) principles; and to increase the rigor and reproducibility of the data collected. Accomplishing these goals will require significant cultural shifts surrounding data management and strategies to develop robust and reliable resources that bridge the technical challenges and gaps in expertise.
Objective:
In this commentary, we examine the current state of managing data and metadata—referred to collectively as (meta)data—in the experimental environmental health sciences. We introduce new tools and resources based on in vivo experiments to serve as examples for the broader field.
Methods:
We discuss previous and ongoing efforts to improve (meta)data collection and curation. These include global efforts by the Functional Genomics Data Society to develop metadata collection tools such as the Investigation, Study, Assay (ISA) framework, and the Center for Expanded Data Annotation and Retrieval. We also conduct a case study of in vivo data deposited in the Gene Expression Omnibus that demonstrates the current state of in vivo environmental health data and highlights the value of using the tools we propose to support data deposition.
Discussion:
The environmental health science community has played a key role in efforts to achieve the goals of the FAIR guiding principles and is well positioned to advance them further. We present a proposed framework to further promote these objectives and minimize the obstacles between data producers and data scientists to maximize the return on research investments.
Details
- Title: Subtitle
- A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data
- Creators
- Rance Nault - Michigan State UniversityMatthew C. Cave - University of LouisvilleGabriele Ludewig - University of IowaHunter N.B. Moseley - University of KentuckyKelly G. Pennell - University of KentuckyTim Zacharewski - Michigan State University
- Resource Type
- Journal article
- Publication Details
- Environmental health perspectives, Vol.131(6), 065001
- DOI
- 10.1289/EHP11484
- PMID
- 37352010
- PMCID
- PMC10289218
- NLM abbreviation
- Environ Health Perspect
- ISSN
- 0091-6765
- eISSN
- 1552-9924
- Publisher
- Environmental Health Perspectives
- Grant note
- This work was supported by the NIEHS Superfund Research Program (SRP) to T.Z. (P42ES004911) and SRP Data Interoperability and Reuse supplements to the Michigan State University Superfund Research Center (SRC) (P42ES004911), the University of Kentucky SRC (P42ES007380), the University of Louisville SRC (P42ES023716), and the University of Iowa SRP (P42ES013661).
- Language
- English
- Date published
- 06/23/2023
- Academic Unit
- Occupational and Environmental Health; Iowa Superfund Research Program
- Record Identifier
- 9984436278302771
Metrics
21 Record Views