A Case of Mild Encephalopathy with a Reversible Splenial Lesion Associated with G5P[6]Rotavirus Infection

Tsuyoshi Matsuoka; Toshifumi Yodoshi; Misaki Sugai; Masato Hiyane; Takashi Matsuoka; Hideki Akeda; Masaharu Ohfu; Satoshi Komoto; Koki Taniguchi

doi:10.1155/2013/197163

Back

A Case of Mild Encephalopathy with a Reversible Splenial Lesion Associated with G5P[6]Rotavirus Infection

Journal article

Open access

Peer reviewed

A Case of Mild Encephalopathy with a Reversible Splenial Lesion Associated with G5P[6]Rotavirus Infection

Tsuyoshi Matsuoka, Toshifumi Yodoshi, Misaki Sugai, Masato Hiyane, Takashi Matsuoka, Hideki Akeda, Masaharu Ohfu, Satoshi Komoto and Koki Taniguchi

Case reports in pediatrics, Vol.2013, 197163

01/01/2013

DOI: 10.1155/2013/197163

PMID: 24324908

Files and links (1)

url

https://doi.org/10.1155/2013/197163View

Published (Version of record) Open Access

Abstract

5 We report a case of mild encephalopathy with a reversible splenial lesion (MERS) associated with acute gastroenteritis caused by rotavirus (RV) infection. The patient (male, 4 years and 3months old) was admitted to our hospital for diarrhea and afebrile seizures. Head MRI revealed a hyperintense signal in the splenium of the corpus callosum on DWI and a hypointense signal on the ADCmap. After awakening from sedation, the patient's disturbance of consciousness improved. On day 5 after admission of the illness, the patient was discharged from the hospital in a good condition. Electroencephalography on day 2 after admission was normal. On day 8 of admission, head MRI revealed that the splenial lesion had disappeared. RV antigen-positive stools suggested that RV had causedMERS. This RV genotype was considered to be G5P[6]; it may have spread to humans as a strain reassortment through substitution of porcineRVinto humanRVgene segments. This extremely rare genotypewas detected first in Japan and is not covered by existing vaccines; this is the first sample isolated from encephalopathy patients. Few reports have investigated RV genotypes in encephalopathy; we believe that this case is valuable for studying the relationship between genotypes and clinical symptoms.

Pediatrics

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: A Case of Mild Encephalopathy with a Reversible Splenial Lesion Associated with G5P[6]Rotavirus Infection
Creators: Tsuyoshi Matsuoka - Nanbu Child Medical Center
Toshifumi Yodoshi - Nanbu Child Medical Center
Misaki Sugai - Nanbu Child Medical Center
Masato Hiyane - Nanbu Child Medical Center
Takashi Matsuoka - Nanbu Child Medical Center
Hideki Akeda - Nanbu Child Medical Center
Masaharu Ohfu - Nanbu Child Medical Center
Satoshi Komoto - Fujita Health University
Koki Taniguchi - Fujita Health University
Resource Type: Journal article
Publication Details: Case reports in pediatrics, Vol.2013, 197163
DOI: 10.1155/2013/197163
PMID: 24324908
NLM abbreviation: Case Rep Pediatr
ISSN: 2090-6803
eISSN: 2090-6811
Publisher: Hindawi Publishing Group
Number of pages: 3
Language: English
Date published: 01/01/2013
Academic Unit: Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
Record Identifier: 9985217141002771

Metrics

2 Record Views

6 Times Cited - Web of Science