Journal article
A Comparison of Category and Letter Fluency in Alzheimer's Disease and Huntington's Disease
Neuropsychology, Vol.8(1), pp.25-30
01/01/1994
DOI: 10.1037/0894-4105.8.1.25
Abstract
Forty-four patients with dementia of the Alzheimer type (DAT), 44 elderly normal control (ENC) Ss demographically matched to the DAT group, 42 patients with Huntington's disease (HD), and 42 middle-aged normal control (MNC) Ss demographically matched to the HD group were administered letter and category fluency tasks. DAT patients showed an overproportional impairment on category than on letter fluency tasks, whereas HD patients were equally impaired. Analyses based on receiver operating characteristic curves revealed that category fluency correctly classified significantly more DAT and ENC subjects than did letter fluency, whereas the two fluency tasks did not differ in this respect for HD and MNC subjects. Results suggest that HD patients' failures on fluency tasks are caused by impaired initiation/retrieval capacities. In contrast, DAT patients' greater category than letter fluency deficits are primarily due to a breakdown in the structure of semantic knowledge.
Details
- Title: Subtitle
- A Comparison of Category and Letter Fluency in Alzheimer's Disease and Huntington's Disease
- Creators
- Andreas U. Monsch - University of San DiegoMark W. Bondi - University of San DiegoNelson Butters - University of San DiegoJane S. Paulsen - University of San DiegoDavid P. Salmon - University of California - San Diego School of MedicinePeter Brugger - University of San DiegoMichael R. Swenson - University of California - San Diego School of Medicine
- Resource Type
- Journal article
- Publication Details
- Neuropsychology, Vol.8(1), pp.25-30
- Publisher
- Amer Psychological Assoc
- DOI
- 10.1037/0894-4105.8.1.25
- ISSN
- 0894-4105
- eISSN
- 1931-1559
- Number of pages
- 6
- Grant note
- Department of Veterans Affairs Medical Research Service; US Department of Veterans Affairs La Roche Foundation postdoctoral fellowship (Switzerland) 823A-030702 / Swiss National Science Foundation; Swiss National Science Foundation (SNSF) AG-05561; AG-05131; AG-08204 / National Institute on Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
- Language
- English
- Date published
- 01/01/1994
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383286002771
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