A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in Diagnosis of Invasive Fungal Infections

J. Stacey Klutts; Barbara Robinson-Dunn

doi:10.1128/JCM.00468-11

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A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in Diagnosis of Invasive Fungal Infections

Journal article

Open access

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A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in Diagnosis of Invasive Fungal Infections

J. Stacey Klutts and Barbara Robinson-Dunn

Journal of clinical microbiology, Vol.49(9 Suppl), pp.S39-S42

09/2011

DOI: 10.1128/JCM.00468-11

PMCID: PMC3185840

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Abstract

The incidence of invasive fungal infections (IFIs) continues to rise in industrialized countries, primarily due to both increasingly potent iatrogenic immunosuppression and immunocompromising therapies aimed at treating hematologic malignancies. As this situation continues to evolve, the clinical microbiology laboratory has few new, innovative methodologies to diagnose these serious infections and existing methods lack sensitivity. This represents a difficult clinical situation for health care providers, as they are left to rely on clinical instincts for the management of patients with potential IFIs, as mycology test results are not consistently reliable. The goals of this session of Camp Clin Micro (CCM) were to critically assess currently available methods and practices for diagnosing IFIs, to discuss the potential of current investigational methods, to evaluate the role of antifungal susceptibility testing, and finally to identify action items that can help move the field of diagnostic mycology in a direction that will improve our ability to identify IFIs in a timely manner. This is meant to be not a comprehensive overview of the diagnosis of IFIs but rather a detailed account of the discussion at CCM among clinical microbiologists with experience in diagnostic mycology and knowledge of the literature.

Proceedings of Camp Clin Micro 2011

Details

Title: Subtitle: A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in Diagnosis of Invasive Fungal Infections
Creators: J. Stacey Klutts - University of Iowa
Barbara Robinson-Dunn - Oakland University
Resource Type: Journal article
Publication Details: Journal of clinical microbiology, Vol.49(9 Suppl), pp.S39-S42
Publisher: American Society for Microbiology
DOI: 10.1128/JCM.00468-11
PMCID: PMC3185840
ISSN: 0095-1137
eISSN: 1098-660X
Language: English
Date published: 09/2011
Academic Unit: Pathology
Record Identifier: 9984186774802771

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