Journal article
A Dynamic System for the Analysis of Acoustic Features and Valence of Aversive Sounds in the Human Brain
BASIC ASPECTS OF HEARING: PHYSIOLOGY AND PERCEPTION, Vol.787, pp.463-472
Advances in Experimental Medicine and Biology
01/01/2013
DOI: 10.1007/978-1-4614-1590-9_51
PMID: 23716253
Abstract
Certain sounds, for example, the squeal of chalk on a blackboard, are perceived as highly unpleasant. Functional magnetic resonance imaging (fMRI) in humans shows responses in the amygdala and auditory cortex to aversive sounds. Dynamic causal modelling (DCM) of the interaction between auditory cortex and the amygdala revealed that evoked responses to aversive sounds are relayed to the amygdala via the auditory cortex. There is a complex interaction between the auditory cortex and amygdala involving effective connectivity in both directions. While acoustic features modulate forward connections from auditory cortex to the amygdala, the valence modulates effective connectivity from the amygdala to the auditory cortex. The results support interaction between the auditory cortex and amygdala where stimuli are first processed to a higher (object) level in the auditory cortex before assignment of valence in the amygdala.
Details
- Title: Subtitle
- A Dynamic System for the Analysis of Acoustic Features and Valence of Aversive Sounds in the Human Brain
- Creators
- Sukhbinder Kumar - Newcastle UniversityKatharina von Kriegstein - Max Planck SocietyKarl J. Friston - Wellcome Centre for Human NeuroimagingTimothy D. Griffiths - Newcastle University
- Contributors
- BCJ Moore (Editor)R D Patterson (Editor)I M Winter (Editor)R P Carlyon (Editor)H E Gockel (Editor)
- Resource Type
- Journal article
- Publication Details
- BASIC ASPECTS OF HEARING: PHYSIOLOGY AND PERCEPTION, Vol.787, pp.463-472
- Publisher
- Springer Nature
- Series
- Advances in Experimental Medicine and Biology
- DOI
- 10.1007/978-1-4614-1590-9_51
- PMID
- 23716253
- eISBN
- 9781461415909; 146141590X
- ISSN
- 0065-2598
- eISSN
- 2214-8019
- Number of pages
- 10
- Grant note
- Wellcome Trust; European Commission
- Language
- English
- Date published
- 01/01/2013
- Academic Unit
- Psychological and Brain Sciences; Neurosurgery
- Record Identifier
- 9984304034002771
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