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A Fatal Case of Non-Uremic Calciphylaxis: A Case Report and Literature Review
Journal article   Open access

A Fatal Case of Non-Uremic Calciphylaxis: A Case Report and Literature Review

Abubaker O. Abdalla, Jaafar Al-Khafaji, Mohamed Taha and Samira Malik
The American journal of case reports, Vol.19, pp.804-807
07/09/2018
DOI: 10.12659/AJCR.909546
PMCID: PMC6066970
PMID: 29983410
url
https://europepmc.org/articles/pmc6066970View
Published (Version of record) Open Access

Abstract

Objective: Rare disease Background: Calciphylaxis is a rare cutaneous disease, also known as calcific uremic arteriolopathy, that occurs most frequently in patients with advanced chronic kidney disease and on long-term hemodialysis. Case Report: We describe the case of a 61-year-old female patient with worsening chronic kidney disease not on dialysis therapy, who presented with severe progressive calciphylaxis on both lower limbs. Conclusions: Calcific uremic arteriolopathy is a rare fatal condition that requires prompt diagnosis and treatment. It is classically described in patients with end-stage kidney disease on long-term renal replacement therapy but can present in patients with an earlier stage of kidney disease. Non-uremic calciphylaxis should be suspected in patients with earlier stages of kidney disease, especially in those with other concurrent risk factors or co-morbid conditions, to avoid the high risk of morbidity and mortality associated with such cases.
General & Internal Medicine Life Sciences & Biomedicine Medicine, General & Internal Science & Technology

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