Journal article
A Lifestyle Intervention Study in Patients with Diabetes or Impaired Glucose Tolerance: Translation of a Research Intervention into Practice
Journal of the American Board of Family Medicine, Vol.22(5), pp.535-543
09/01/2009
DOI: 10.3122/jabfm.2009.05.090012
PMID: 19734400
Abstract
Objective: The objectives of this study were to translate a research-validated lifestyle modification curriculum of the Diabetes Prevention Program (DPP) into a community-based program delivered by trained graduate students on a university campus and determine whether this delivery approach is effective in lowering risk factors of type 2 diabetes in at-risk adults.
Methods: A convenience sample of 29 prediabetic or type 2 diabetic patients completed a 12-month behavior modification intervention to achieve and maintain at least 7% weight loss and become more active. Changes in weight, waist and hip circumferences, blood pressure, metabolic biomarkers, physical activity levels, and medication were assessed.
Results: At 6 and 12 months, 39% and 56% of patients had lost >= 5% of their weight. The mean weight loss at 12 months was 6%. Significant improvements were noted in most other anthropometric measurements and diastolic BP (-4.1 mm Hg). Significant reductions in total cholesterol (-11.7%), LDL-C (-7.6%), and HDL-C (-6.5%) were observed by 6 months but not at 12 months. Fasting glucose (12%), systolic BP (-8.4 mm Hg), and diastolic BP (-7.0 mm Hg) were significantly improved in a subgroup of participants with at least 5% weight loss. HbA1c levels were associated with percentage weight loss. Twenty-seven percent of participants on diabetes medication had their drug discontinued.
Conclusion: Weight-related findings of this study are comparable with those of the DPP. DPP curriculum implemented in a nonclinical setting can help some adults at-risk for or in early stages of diabetes improve anthropometric and certain metabolic outcomes. (J Am Board Fam Med 2009; 22: 535-543.)
Details
- Title: Subtitle
- A Lifestyle Intervention Study in Patients with Diabetes or Impaired Glucose Tolerance: Translation of a Research Intervention into Practice
- Creators
- Oksana A. Matvienko - University of Northern IowaJames D. Hoehns - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of the American Board of Family Medicine, Vol.22(5), pp.535-543
- Publisher
- Amer Board Family Medicine
- DOI
- 10.3122/jabfm.2009.05.090012
- PMID
- 19734400
- ISSN
- 1557-2625
- eISSN
- 1558-7118
- Number of pages
- 9
- Grant note
- 2007-01-05 / Wellmark Foundation The Wellmark Foundation
- Language
- English
- Date published
- 09/01/2009
- Academic Unit
- Pharmacy Practice and Science
- Record Identifier
- 9984366017402771
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