Journal article
A Multiscale Model of Biofilm as a Senescence-Structured Fluid
Multiscale modeling & simulation, Vol.6(2), pp.347-365
09/13/2006
DOI: 10.1137/060669796
Abstract
Multiscale Modeling & Simulation, Vol. 6, No. 2, pp. 347-365, 2007 We derive a physiologically structured multiscale model for biofilm development. The model has components on two spatial scales, which induce different time scales into the problem. The macroscopic behavior of the system is modeled using growth-induced flow in a domain with a moving boundary. Cell-level processes are incorporated into the model using a so-called physiologically structured variable to represent cell senescence, which in turn affects cell division and mortality. We present computational results for our models which shed light on modeling the combined role senescence and the biofilm state play in the defense strategy of bacteria.
Details
- Title: Subtitle
- A Multiscale Model of Biofilm as a Senescence-Structured Fluid
- Creators
- Bruce P AyatiIsaac Klapper
- Resource Type
- Journal article
- Publication Details
- Multiscale modeling & simulation, Vol.6(2), pp.347-365
- DOI
- 10.1137/060669796
- ISSN
- 1540-3459
- eISSN
- 1540-3467
- Language
- English
- Date published
- 09/13/2006
- Academic Unit
- Orthopedics and Rehabilitation; Mathematics
- Record Identifier
- 9983985935202771
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