Journal article
A New Brief Clinical Assessment of Lower Urinary Tract Symptoms for Women and Men: LURN SI-10
The Journal of urology, Vol.203(1), pp.164-170
01/01/2020
DOI: 10.1097/JU.0000000000000465
PMCID: PMC6904437
PMID: 31364922
Abstract
Purpose: Lower urinary tract symptoms are common in men and women. Members of the LURN (Lower Urinary Tract Dysfunction Research Network) sought to create a brief, clinically relevant tool to improve existing measurements of lower urinary tract symptoms in men and women.
Materials and Methods: Using a modified Delphi methodology during an expert consensus meeting we reduced the LURN CASUS (Comprehensive Assessment of Self-Reported Urinary Symptoms) questionnaire to a brief set of clinically relevant items measuring lower urinary tract symptoms. The sum score of these items was evaluated by comparing it to the AUA SI (American Urological Association Symptom Index), the UDI-6 (Urinary Distress Inventory Short Form) in women only and the CASUS lower urinary tract symptoms screening questions using the Pearson correlation, regression analysis and ROC curves.
Results: The LURN SI-10 (10-Item LURN Symptom Index) assesses urinary frequency, nocturia, urgency, incontinence, bladder pain, voiding and post-micturition symptoms (score range 0 to 38). The correlation between LURN SI-10 and AUA SI scores was 0.77 in men and 0.70 in women. The UDI-6 and the LURN SI-10 correlated highly in women (r=0.76). The LURN SI-10 showed good accuracy to predict moderate and severe lower urinary tract symptoms as defined by the AUA SI (ROC AUC range 0.82-0.90). Similar accuracy was shown in predicting different levels of symptom status using the UDI-6 (AUC range 0.84-0.86).
Conclusions: The LURN SI-10 correlates well with the AUA SI and the UDI-6. It includes items related to a broader spectrum of lower urinary tract symptoms, particularly incontinence, bladder pain and post-micturition symptoms, and it applies to men and women.
Details
- Title: Subtitle
- A New Brief Clinical Assessment of Lower Urinary Tract Symptoms for Women and Men: LURN SI-10
- Creators
- David Cella - Northwestern UniversityAbigail R. Smith - Arbor Research Collaborative for HealthJames W. Griffith - Northwestern UniversityZiya Kirkali - National Institute of Diabetes and Digestive and Kidney DiseasesKathryn E. Flynn - Medical College of WisconsinCatherine S. Bradley - University of IowaJ. Eric Jelovsek - #N#†Duke University Medical Center, Durham, North CarolinaBrenda W. Gillespie - University of Michigan–Ann ArborBrian T. Helfand - NorthShore University HealthSystemPooja Talaty - NorthShore University HealthSystemKevin P. Weinfurt - #N#†Duke University Medical Center, Durham, North CarolinaLower Urinary Tract Dysfunction Research Network (LURN) Study Group
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.203(1), pp.164-170
- DOI
- 10.1097/JU.0000000000000465
- PMID
- 31364922
- PMCID
- PMC6904437
- NLM abbreviation
- J Urol
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 7
- Grant note
- DK097780; DK097772; DK097779; DK099932; DK100011; DK100017; DK097776; DK099879; UL1TR001422 / NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) at Northwestern University by NIH (National Institutes of Health) NCATS (National Center for Advancing Translational Sciences) K23-DK110417 / NIDDK; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
- Language
- English
- Date published
- 01/01/2020
- Academic Unit
- Epidemiology; Obstetrics and Gynecology; Urology
- Record Identifier
- 9984315564402771
Metrics
20 Record Views