Journal article
A Pilot Study of the Use of Biocide-Impregnated Gauze as an Adjunct to Wound Care in a Burn Population
Journal of burn care & research, Vol.33(3), pp.358-363
05/01/2012
DOI: 10.1097/BCR.0b013e31823746d2
PMID: 22210061
Abstract
The aim of this study was to evaluate the use of a polyhexamethylene biguanide biocide-impregnated gauze (Kerlix (TM) AMD gauze dressing, Covidien d/b/a Tyco Healthcare Group LP) as an adjuvant to routine burn care and its impact on the incidence of hospital-associated infections in burn population. One hundred eight burn patients admitted to the Burn Treatment Center were prospectively enrolled from August 2008 to June 2009 and matched 1: 2 with historic controls who were admitted from March 2006 to July 2008. Clinical care remained otherwise unchanged; however, several hospital initiatives (the national surgical improvement project, the surgical care improvement project, and a central venous line bundle) were initiated before and during the study. There were significantly less infections in the study population (18.52% of case patients vs 28.70% of control patients had infections, P = .047). Although there was a decrease in each infection subtype analyzed, a statistically significant reduction was only reached for pneumonias (1.85% in cases vs 5.86 in controls, P = .042). Implementation of polyhexamethylene biguanide biocide-impregnated gauze was temporally correlated with a significant decrease in healthcare-associated infections in burn population. As there was no corresponding decrease in wound infections, the impact of the gauze on healthcare-associated infections, if any, cannot be conclusively determined by this study. A larger prospective study powered to detect a decrease in wound-related infections is warranted. (J Burn Care Res 2012;33:358-363)
Details
- Title: Subtitle
- A Pilot Study of the Use of Biocide-Impregnated Gauze as an Adjunct to Wound Care in a Burn Population
- Creators
- Lucy Wibbenmeyer - Roy J. and Lucille A. Carver College of MedicineIngrid Williams - Roy J. and Lucille A. Carver College of MedicineJunlin Liao - University of IowaJason Heard - Roy J. and Lucille A. Carver College of MedicineGerald Patrick Kealey - University of IowaRachel Miller - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Journal of burn care & research, Vol.33(3), pp.358-363
- DOI
- 10.1097/BCR.0b013e31823746d2
- PMID
- 22210061
- NLM abbreviation
- J Burn Care Res
- ISSN
- 1559-047X
- eISSN
- 1559-0488
- Publisher
- Oxford Univ Press
- Number of pages
- 6
- Grant note
- Covidien d/b/a Tyco Healthcare Group LP
- Language
- English
- Date published
- 05/01/2012
- Academic Unit
- Surgery; Injury Prevention Research Center
- Record Identifier
- 9984322949602771
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