Journal article
A Randomized Controlled Trial of High-Viscosity 2-Octyl Cyanoacrylate Tissue Adhesive versus Sutures in Repairing Facial Wounds Following Mohs Micrographic Surgery
Dermatologic surgery, Vol.33(8), pp.966-971
08/2007
DOI: 10.1111/j.1524-4725.2007.33199.x
PMID: 17661940
Abstract
BACKGROUNDHigh-viscosity 2-octyl cyanoacrylate (HVOCA) is a rapidly polymerizing liquid topical adhesive indicated for epidermal approximation of superficial lacerations and surgical wounds. Use of HVOCA in repair of facial wounds after Mohs micrographic surgery (MMS) has not been reported.
OBJECTIVETo compare aesthetic outcome of HVOCA versus sutured epidermal closure of linearly repaired facial wounds following MMS.
METHODSPatients undergoing MMS for facial tumors with postoperative wounds >3 cm appropriate for linear closure were recruited. After placement of dermal sutures, half the wound was randomly selected for closure with HVOCA and the other half was closed with 5-0 polypropylene suture.
RESULTSFourteen patients (13 men and 1 woman; mean age, 72±8.8 years; range, 52–81 years) with basal cell or squamous cell carcinoma of the face (n=12) or neck (n=2) were enrolled. The mean wound length was 4.9±1.9 cm (range, 3.1–10 cm). No postoperative complications, including bleeding, infection, or dehiscence, occurred. Using photographs obtained 3 months postoperatively, five dermatologists (including two Mohs surgeons) blinded to the intervention rated cosmesis using a visual analog scale from 1 (worst) to 10 (best). The mean ratings for HVOCA half (6.64±1.55) versus sutured half (6.77±1.88) were not significantly different (p=.35). Paired comparisons of rater preferences similarly showed no cosmetic differences. All 14 patients preferred OCA for ease of postoperative care.
CONCLUSIONHVOCA tissue adhesive is cosmetically equivalent to epidermal sutures in the linear repair of facial wounds following MMS. This technique represents an additional option for Mohs surgeons.
Details
- Title: Subtitle
- A Randomized Controlled Trial of High-Viscosity 2-Octyl Cyanoacrylate Tissue Adhesive versus Sutures in Repairing Facial Wounds Following Mohs Micrographic Surgery
- Creators
- PATRICK SNIEZEK - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaHOBART WALLING - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaJAMES DEBLOOM - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaMICHAEL MESSINGHAM - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaMARTA VANBEEK - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaCLARENCE KREITER - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaDUANE WHITAKER - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, IowaCHRISTOPHER ARPEY - Department of Dermatology and Department of Biostatistics, University of Iowa Hospitals and Clinics, and Veteran Affairs Hospital, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Dermatologic surgery, Vol.33(8), pp.966-971
- Publisher
- by the American Society for Dermatologic Surgery, Inc
- DOI
- 10.1111/j.1524-4725.2007.33199.x
- PMID
- 17661940
- ISSN
- 1076-0512
- eISSN
- 1524-4725
- Language
- English
- Date published
- 08/2007
- Academic Unit
- Dermatology; Family and Community Medicine
- Record Identifier
- 9984025276002771
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