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A Rare Case of Cephalosporin Anaphylaxis-Induced Reverse Takotsubo
Journal article   Open access   Peer reviewed

A Rare Case of Cephalosporin Anaphylaxis-Induced Reverse Takotsubo

Omer Farooq, Roger Lin, Benjamin Easow, Paarmit Chhabra and Paramjit Kaur
Curēus (Palo Alto, CA), Vol.16(7), e63987
07/06/2024
DOI: 10.7759/cureus.63987
PMCID: PMC11300078
PMID: 39104965
url
https://doi.org/10.7759/cureus.63987View
Published (Version of record) Open Access

Abstract

This case report details an unusual occurrence of reverse takotsubo induced by cefazolin anaphylaxis. While anaphylactic reactions typically manifest with hypotension and bronchospasm, the development of takotsubo is a rare outcome. The patient experienced an episode of cefazolin-induced anaphylaxis during elective shoulder surgery, subsequently developing reverse takotsubo cardiomyopathy (rTTC) during her hospitalization. Initial testing showed a reduced heart function, with an ejection fraction (EF) dropping to 32% from a previously normal EF exceeding 50%. However, a follow-up heart catheterization three weeks later revealed a return to normal heart function. The patient received appropriate management for heart failure. By emphasizing the nuanced features and symptoms, we aim to enhance the recognition and management of this condition. Sharing such cases contributes to the medical community's knowledge and facilitates the advancement of strategies for diagnosing and managing anaphylaxis-induced reverse takotsubo.
 Cardiology Internal Medicine Allergy/Immunology

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