A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups

Sheenah M. Mische; Nancy C. Fisher; Susan M. Meyn; Katia Sol-Church; Rebecca L. Hegstad-Davies; Frances Weis-Garcia; Marie Adams; John M. Ashton; Kym M. Delventhal; Julie A. Dragon; Laura Holmes; Pratik Jagtap; Kristopher E. Kubow; Christopher E. Mason; Magnus Palmblad; Brian C. Searle; Christoph W. Turck; Kevin L. Knudtson

doi:10.7171/jbt.20-3101-003

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A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups

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A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups

Sheenah M. Mische, Nancy C. Fisher, Susan M. Meyn, Katia Sol-Church, Rebecca L. Hegstad-Davies, Frances Weis-Garcia, Marie Adams, John M. Ashton, Kym M. Delventhal, Julie A. Dragon, …

Journal of biomolecular techniques, Vol.31(1), pp.11-26

04/01/2020

DOI: 10.7171/jbt.20-3101-003

PMCID: PMC6959150

PMID: 31969795

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Abstract

Shared research resource facilities, also known as core laboratories (Cores), are responsible for generating a significant and growing portion of the research data in academic biomedical research institutions. Cores represent a central repository for institutional knowledge management, with deep expertise in the strengths and limitations of technology and its applications. They inherently support transparency and scientific reproducibility by protecting against cognitive bias in research design and data analysis, and they have institutional responsibility for the conduct of research (research ethics, regulatory compliance, and financial accountability) performed in their Cores. The Association of Biomolecular Resource Facilities (ABRF) is a FASEB-member scientific society whose members are scientists and administrators that manage or support Cores. The ABRF Research Groups (RGs), representing expertise for an array of cutting-edge and established technology platforms, perform multicenter research studies to determine and communicate best practices and community-based standards. This review provides a summary of the contributions of the ABRF RGs to promote scientific rigor and reproducibility in Cores from the published literature, ABRF meetings, and ABRF RGs communications.

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Title: Subtitle: A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups
Creators: Sheenah M. Mische - NYU Langone Health
Nancy C. Fisher - University of North Carolina at Chapel Hill
Susan M. Meyn - Vanderbilt University Medical Center
Katia Sol-Church - University of Virginia
Rebecca L. Hegstad-Davies - University of Minnesota
Frances Weis-Garcia - Memorial Sloan Kettering Cancer Center
Marie Adams - Van Andel Institute
John M. Ashton - University of Rochester Medical Center
Kym M. Delventhal - Stowers Institute for Medical Research
Julie A. Dragon - University of Vermont
Laura Holmes - Stowers Institute for Medical Research
Pratik Jagtap - University of Minnesota
Kristopher E. Kubow - James Madison University
Christopher E. Mason - Cornell University
Magnus Palmblad - Leiden University Medical Center
Brian C. Searle - Institute for Systems Biology
Christoph W. Turck - Max Planck Institute of Psychiatry
Kevin L. Knudtson - University of Iowa
Resource Type: Journal article
Publication Details: Journal of biomolecular techniques, Vol.31(1), pp.11-26
DOI: 10.7171/jbt.20-3101-003
PMID: 31969795
PMCID: PMC6959150
NLM abbreviation: J Biomol Tech
ISSN: 1524-0215
eISSN: 1943-4731
Publisher: Association of Biomolecular Resource Facilities
Language: English
Date published: 04/01/2020
Academic Unit: Iowa Institute of Human Genetics
Record Identifier: 9984627296202771

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