Journal article
A Roadmap for Innovation to Advance Transplant Access and Outcomes: A Position Statement From the National Kidney Foundation
American journal of kidney diseases, Vol.78(3), pp.319-332
09/01/2021
DOI: 10.1053/j.ajkd.2021.05.007
PMID: 34330526
Abstract
Over the past 65 years, kidney transplantation has evolved into the optimal treatment for patients with kidney failure, dramatically reducing suffering through improved survival and quality of life. However, access to transplant is still limited by organ supply, opportunities for transplant are inequitably distributed, and lifelong transplant survival remains elusive. To address these persistent needs, the National Kidney Foundation convened an expert panel to define an agenda for future research. The key priorities identified by the panel center on the needs to develop and evaluate strategies to expand living donation, improve waitlist management and transplant readiness, maximize use of available deceased donor organs, and extend allograft longevity. Strategies targeting the critical goal of decreasing organ discard that warrant research investment include educating patients and clinicians about potential benefits of accepting nonstandard organs, use of novel organ assessment technologies and real-time decision support, and approaches to preserve and resuscitate allografts before implantation. The development of personalized strategies to reduce the burden of lifelong immunosuppression and support "one transplant for life" was also identified as a vital priority. The panel noted the specific goal of improving transplant access and graft survival for children with kidney failure. This ambitious agenda will focus research investment to promote greater equity and efficiency in access to transplantation, and help sustain long-term benefits of the gift of life for more patients in need.
Details
- Title: Subtitle
- A Roadmap for Innovation to Advance Transplant Access and Outcomes: A Position Statement From the National Kidney Foundation
- Creators
- Krista L. Lentine - St Louis Univ, Ctr Abdominal Transplantat, 1201 S Grand Blvd, St Louis, MO 63104 USAStephen Pastan - Emory and Henry CollegeSumit Mohan - Columbia University Irving Medical CenterPeter P. Reese - University of PennsylvaniaAlan Leichtman - University of MichiganFrancis L. Delmonico - New England Organ BankGabriel M. Danovitch - University of California, Los AngelesChristian P. Larsen - Emory and Henry CollegeLyndsay Harshman - University of IowaAlexander Wiseman - Porter Adventist HospitalHolly J. Kramer - Loyola University ChicagoJoseph Vassalotti - Icahn School of Medicine at Mount SinaiJessica Joseph - National Kidney FoundationKevin Longino - National Kidney FoundationMatthew Cooper - Department of Surgery, Medstar Georgetown Transplant Institute, Washington, DC.David A. Axelrod - University of IowaNational Kidney Foundation
- Resource Type
- Journal article
- Publication Details
- American journal of kidney diseases, Vol.78(3), pp.319-332
- DOI
- 10.1053/j.ajkd.2021.05.007
- PMID
- 34330526
- NLM abbreviation
- Am J Kidney Dis
- ISSN
- 0272-6386
- eISSN
- 1523-6838
- Publisher
- Elsevier
- Number of pages
- 14
- Grant note
- National Kidney Foundation
- Language
- English
- Date published
- 09/01/2021
- Academic Unit
- Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Surgery; Radiation Oncology
- Record Identifier
- 9984322824502771
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