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A Systematic Review of Pediatric Phase I Trials in Oncology: Toxicity and Outcomes in the Era of Targeted Therapies
Journal article   Open access   Peer reviewed

A Systematic Review of Pediatric Phase I Trials in Oncology: Toxicity and Outcomes in the Era of Targeted Therapies

Julia W. Cohen, Srivandana Akshintala, Eli Kane, Helen Gnanapragasam, Brigitte C. Widemann, Seth M. Steinberg and Nirali N. Shah
The oncologist (Dayton, Ohio), Vol.25(6), pp.532-540
01/14/2020
DOI: 10.1634/theoncologist.2019-0615
PMCID: PMC7288652
PMID: 31943534
url
https://doi.org/10.1634/theoncologist.2019-0615View
Published (Version of record) Open Access

Abstract

This systematic review of pediatric oncology phase I trials describes the safety profile and response outcomes from recent trials, comparing cytotoxic and targeted trials in the era of targeted therapies.
26 44 Outcome Pediatric Oncology Phase I Systematic review Targeted therapy Toxicity

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