Journal article
A biorepository for ophthalmic surgical specimens
Proteomics. Clinical applications, Vol.8(3-4), pp.209-217
04/2014
DOI: 10.1002/prca.201300043
PMCID: PMC3964151
PMID: 24115637
Abstract
Biorepositories are collections of surgically obtained human tissues for current and future investigations of disease mechanisms, therapeutics, and diagnostics. In ophthalmology, a critical challenge is how to interface the operating room with the laboratory. To attain standards required for basic research, clinical and research teams must cooperate to collect, annotate, and store specimens that yield consistent results required for advanced molecular techniques. We developed an efficient platform for obtaining vitreous and other eye tissues from the operating room and transferring them to the lab. The platform includes a mobile lab cart for on-site tissue processing, a multi-user, web-based database for point-of-care phenotypic capture, and an integrated data tracking system for long-term storage. These biorepository instruments have proven essential for our studies in ophthalmic disease proteomics. This system can be implemented in other operating rooms and laboratories for a variety of biological tissues.
Details
- Title: Subtitle
- A biorepository for ophthalmic surgical specimens
- Creators
- Jessica M. Skeie - University of IowaStephen H. Tsang - University of IowaRyan Vande Zande - Univ Iowa, Dept Ophthalmol & Visual Sci, Iowa City, IA 52242 USAMacy M. Fickbohm - University of IowaShaival S. Shah - University of IowaJohn G. Vallone - University of Southern CaliforniaVinit B. Mahajan - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Proteomics. Clinical applications, Vol.8(3-4), pp.209-217
- Publisher
- Wiley
- DOI
- 10.1002/prca.201300043
- PMID
- 24115637
- PMCID
- PMC3964151
- ISSN
- 1862-8346
- eISSN
- 1862-8354
- Number of pages
- 9
- Grant note
- 1K08EY020530-01A1; 1F32EY022280-01A1 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R01EY018213 / NATIONAL EYE INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) Research to Prevent Blindness; Research to Prevent Blindness (RPB)
- Language
- English
- Date published
- 04/2014
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984627236602771
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