A cascade cyclization approach to schweinfurthin B

Edward M Treadwell; Jeffrey D Neighbors; David F Wiemer

doi:10.1021/ol0266368

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A cascade cyclization approach to schweinfurthin B

Journal article

Peer reviewed

A cascade cyclization approach to schweinfurthin B

Edward M Treadwell, Jeffrey D Neighbors and David F Wiemer

Organic letters, Vol.4(21), pp.3639-3642

10/17/2002

DOI: 10.1021/ol0266368

PMID: 12375907

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Abstract

[reaction: see text] A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phenylselenide substituent for an equatorial orientation.

Models, Molecular

Molecular Structure

Stilbenes - chemistry

Magnetic Resonance Spectroscopy

Stereoisomerism

Details

Title: Subtitle: A cascade cyclization approach to schweinfurthin B
Creators: Edward M Treadwell - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA
Jeffrey D Neighbors
David F Wiemer
Resource Type: Journal article
Publication Details: Organic letters, Vol.4(21), pp.3639-3642
Publisher: United States
DOI: 10.1021/ol0266368
PMID: 12375907
ISSN: 1523-7060
eISSN: 1523-7052
Language: English
Date published: 10/17/2002
Academic Unit: Neuroscience and Pharmacology; Chemistry
Record Identifier: 9983985959802771

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