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A case of clozapine-induced neuroleptic malignant syndrome
Journal article   Peer reviewed

A case of clozapine-induced neuroleptic malignant syndrome

D D Miller, M J Sharafuddin and R G Kathol
The journal of clinical psychiatry, Vol.52(3), pp.99-101
03/1991
PMID: 1672311

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Abstract

The treatment of psychotic symptoms in patients with a previous history of neuroleptic malignant syndrome (NMS) remains a dilemma. The authors describe a case in which clozapine caused NMS in a schizophrenic man who had previously experienced NMS during treatment with various antipsychotics. To their knowledge, this is the first report of "classical" NMS caused by clozapine alone.
Schizophrenia, Catatonic - drug therapy Antipsychotic Agents - adverse effects Humans Middle Aged Neuroleptic Malignant Syndrome - etiology Male Dantrolene - therapeutic use Clozapine - adverse effects Neuroleptic Malignant Syndrome - drug therapy Schizophrenia, Catatonic - psychology

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