A case of primary cutaneous Ewing sarcoma in a neutropenic patient

Zoe O Brown-Joel; Andrew M Bellizzi; Benjamin W Darbro; Anthony N Snow; Munir R Tanas; Matthew E Keeney; Mary S Stone; Karolyn A Wanat; Gretchen M Roth

doi:10.1111/cup.13406

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A case of primary cutaneous Ewing sarcoma in a neutropenic patient

Journal article

Peer reviewed

A case of primary cutaneous Ewing sarcoma in a neutropenic patient

Zoe O Brown-Joel, Andrew M Bellizzi, Benjamin W Darbro, Anthony N Snow, Munir R Tanas, Matthew E Keeney, Mary S Stone, Karolyn A Wanat and Gretchen M Roth

Journal of cutaneous pathology, Vol.46(3), pp.238-241

03/2019

DOI: 10.1111/cup.13406

PMID: 30582191

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Abstract

Primary cutaneous Ewing sarcoma is a rare clinical presentation of Ewing sarcoma, usually occurring as a small, localized tumor on the extremities of young adults and associated with favorable prognosis. We report a case of primary cutaneous Ewing sarcoma, which presented on the sole of the foot of a 27-year-old patient with relapsed acute myeloid leukemia and neutropenia. Diagnosis was determined through histological features and staining, as well as fluorescence in situ hybridization and molecular testing. The patient underwent wide-local excision with plan to begin targeted chemotherapy, but unfortunately died from adenovirus pneumonia while neutropenic before targeted chemotherapy was initiated.

Neutropenia - complications

Skin Neoplasms - immunology

Humans

Adult

Female

Immunocompromised Host

Leukemia, Myeloid, Acute - complications

Sarcoma, Ewing - immunology

Details

Title: Subtitle: A case of primary cutaneous Ewing sarcoma in a neutropenic patient
Creators: Zoe O Brown-Joel - Department of Dermatology, University of Iowa Carver College of Medicine, Iowa City, Iowa
Andrew M Bellizzi - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Benjamin W Darbro - Department of Pediatrics-Medical Genetics, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Anthony N Snow - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Munir R Tanas - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Matthew E Keeney - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Mary S Stone - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Karolyn A Wanat - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Gretchen M Roth - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Journal of cutaneous pathology, Vol.46(3), pp.238-241
Publisher: United States
DOI: 10.1111/cup.13406
PMID: 30582191
ISSN: 0303-6987
eISSN: 1600-0560
Grant note: P30 CA086862 / NCI NIH HHS
Language: English
Date published: 03/2019
Academic Unit: Dermatology; Stead Family Department of Pediatrics; Pathology; Medical Genetics and Genomics
Record Identifier: 9984047625102771

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