Journal article
A case of severe eosinophilia in a preterm infant
Pediatrics (Evanston), Vol.127(3), pp.e767-e771
03/2011
DOI: 10.1542/peds.2010-0260
PMID: 21357337
Abstract
Eosinophilia of prematurity is commonly seen in premature infants as a result of many causes, although a sustained or progressive form is uncommon. Different pathophysiological hypotheses include decreased circulating adrenal steroids and foreign antigen exposure. We present here a case of prolonged extreme eosinophilia in a preterm infant complicated by thrombocytopenia. The patient's eosinophil count reached 91.48 × 10(9)/L and remitted with nonspecific treatment. A comprehensive clinical, laboratory, and radiologic assessment is usually required in the context of a hypereosinophilic preterm infant to recognize the triggering etiology. Nonspecific treatment was the modality of choice because of unclear etiology in our case. Preterm infants with blood eosinophilia might not need immunomodulatory treatment despite extremely high absolute eosinophil counts.
Details
- Title: Subtitle
- A case of severe eosinophilia in a preterm infant
- Creators
- Abdul R Shahein - Division of aHematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, CanadaSilvio GonzalezManuel CarcaoMohamed AbdelhaleemJonathan HellmannPatrick J McNamara
- Resource Type
- Journal article
- Publication Details
- Pediatrics (Evanston), Vol.127(3), pp.e767-e771
- DOI
- 10.1542/peds.2010-0260
- PMID
- 21357337
- NLM abbreviation
- Pediatrics
- ISSN
- 0031-4005
- eISSN
- 1098-4275
- Publisher
- American Academy of Pediatrics
- Language
- English
- Date published
- 03/2011
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984093326402771
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