A case series involving young children presenting with accidental ingestion of amphetamine based stimulants

Kelly E Wood; Patrick J McCarthy; Matthew D Krasowski

doi:10.1016/j.toxrep.2018.11.001

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A case series involving young children presenting with accidental ingestion of amphetamine based stimulants

Journal article

Open access

Peer reviewed

A case series involving young children presenting with accidental ingestion of amphetamine based stimulants

Kelly E Wood, Patrick J McCarthy and Matthew D Krasowski

Toxicology reports, Vol.5, pp.1129-1133

2018

DOI: 10.1016/j.toxrep.2018.11.001

PMCID: PMC6258139

PMID: 30510906

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Abstract

• Attention Deficity Hyperactivity Disorder (ADHD) affects adults and children. • Stimulant prescribing for ADHD is increasing. • Overdose of amphetamine based stimulants results in a sympathomimetic toxidrome. • Lisdexamfetamine dimesylate is the first prodrug stimulant developed to treat ADHD.

ADHD, attention deficit hyperactivity disorder

BPM, beats per minute

BMP, basic metabolic panel

MDA, methylenedioxyamphetamine

A, not applicable

MS, liquid chromatography

ELISA, enzyme-linked immunosorbent assay

L, milliequivalents per liter

d-amphetamine, dextroamphetamine

tandem mass spectrometry

5-HT, serotonin

mass spectrometry

MDEA, methylenedioxyethylamphetamine

mL, nanogram per milliliter

CK, creatinine kinase

DSM-V, Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition

QNS, quantity not sufficient

HPLC

THC, tetrahydrocannabinol

MS, gas chromatography

MDMA, methylenedioxymethamphetamine

C, Celsius

EKG, electrocardiogram

FDA, Food and Drug Administration

U.S., United States

MS, high performance liquid chromatography

UDS, urine drug screen

ED, emergency department

mg, milligram

CBC, complete blood count

LDX, lisdexamfetamine dimesylate

mEq

UA, urinalysis

AG, anion gap

mg, picogram per milligram

Details

Title: Subtitle: A case series involving young children presenting with accidental ingestion of amphetamine based stimulants
Creators: Kelly E Wood - Stead Family Department of Pediatrics, University of Iowa Stead Family Children’s Hospital, Iowa City, IA, 52242, USA
Patrick J McCarthy - Stead Family Department of Pediatrics, University of Iowa Stead Family Children’s Hospital, Iowa City, IA, 52242, USA
Matthew D Krasowski - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA
Resource Type: Journal article
Publication Details: Toxicology reports, Vol.5, pp.1129-1133
DOI: 10.1016/j.toxrep.2018.11.001
PMID: 30510906
PMCID: PMC6258139
NLM abbreviation: Toxicol Rep
ISSN: 2214-7500
eISSN: 2214-7500
Publisher: Elsevier
Language: English
Date published: 2018
Academic Unit: Stead Family Department of Pediatrics; Pathology; Hospital Medicine
Record Identifier: 9984047787602771

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