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A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection
Journal article   Peer reviewed

A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection

Lok-Yin Roy Wong and Stanley Perlman
Science immunology, Vol.9(97), eadp8170
07/12/2024
DOI: 10.1126/sciimmunol.adp8170

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Abstract

Upon SARS-CoV-2 infection, infected cells undergo necroptosis, whereas delayed apoptosis and pyroptosis occur in uninfected, bystander cells, thus providing a plausible explanation for the extensive injury among myriad uninfected cells.Upon SARS-CoV-2 infection, infected cells undergo necroptosis, whereas delayed apoptosis and pyroptosis occur in uninfected, bystander cells, thus providing a plausible explanation for the extensive injury among myriad uninfected cells.

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